Lycopene is a red-colored carotenoid with specific application as feed supplement and nutrient in human diets because of its potential in alleviating chronic diseases such as certain cancers and coronary heart disease,as such it is considered to be a potent anti-carcinogenic agent and antioxidant.Blakeslea trispora is convenient for large-scale production in fermentor due to its high growth rate and low nutritional needs.This paper mainly discussed various of fermentation accelerant used on lycopene production by Blakeslea trispora.Accelerants are classified into eight major types according to the mechanism.