This paper discussed the use of waste beer yeast to produce cell wall polysaccharides with catalytic autolysis and cell wall deconstruction technology.Through single factor experiments,the best autolysis efficiency of the yeast were as follows: 50～60℃,pH 5.0～6.0,0.8% NaCl and 200 mg/L VB 2,solid-liquid ratio 1∶(8～10),shearing treatment at least 9h.Also,the best extraction conditions for extraction polysaccharide were: 60℃,solidliquid ratio 1 /10,0.02%～0.03% protease and 2% NaOH.In this method,we can get at least 22% poly-mannose and 35% poly-glucan from the cell wall polysaccharides.Sodium casein and modified starch combination was the best microencapsulated material due to its good spray effect and moisture resistance.