Purpose: The changes of technological parameters in the process of instant black tea by oxygen were investigated.Methods: On the basis of one-factor-at-a-time experiments,solution pH,reaction temperature,solution concentration,reaction time were chosen as the influence factors.The extraction technology was optimized by response surface methodology combined with desirability function analysis.Results:The optimum conditions were determined as:20% of tea solution at pH 9.5 and 80℃ for 20min.Model predicted that under the optimum conditions,the satisfaction expectation D value was 0.831,three verification test mean value was 0.819,which was close to the predicted value.Conclusion: response surface methodologycombined with desirability function analysis is feasible in optimization of oxidation processing conditions for instant black tea.