Flavonoids from orange peel were extracted with 75% alcohol.Effect of common food additives on antioxidation activity of flavonoids from orange peel was studied by DPPH method.The result showed that vitamin C, Sorbic Acid and Citric Acid can improve 36.5%,6.3%,2.2% of inhibition rate of flavonoids from orange peel,respectively.Benzoic acid,sodium propionate and lactic acid can reduce inhibition rate of flavonoids from orange peel.Therefore,vitamin C,sorbic acid and citric acid can improve the antioxidation activity of flavonoids from orange peel.