To understand the phenolic compounds and antioxidant activities of Cabernet Sauvignon and Merlot berries,providing some theoretical evidence for wine-grape from four different region(Yuquanying of Ningxia,Xiangning of Shanxi,Changli and Shacheng of Hebei),the physicochemical index,the phenolic content,antioxidant activities and individual anthocyanin concentration of two kinds of grapes were analyzed.The results showed that the contents of total phenolic,flavonoids,flavanols and anthocyanins compounds and antioxidant capacity of Yuquanying grape were the highest,Shacheng of Hebei took the second place,the other two regions were varied;the total 22 and23 individual anthocyanin compounds from Cabernet Sauvignon and Merlot berries were identified,including 5 basic anthocyanins and 18 individual anthocyanin deriatives;effect of ecological condition on individual anthocyanin composition mainly reflected in anthocyanin deriatives,and the grape variety factor had significantly effect on concentration of individual anthocyanin compounds.So the ecological condition of territory could influence the phenolic content and anthocyanin composition.