The antioxidant activities of extract from different alcohol level Nvzhenzi wine were determined by DPPH·,salicylic acid and pyrogallol auto-oxidation assay. Colorimetry and HPLC were applied to detect the extraction rates of total flavonoids,luteolin and apigenin in Nvzhenzi wine. Results showed that the scavenging effects on DPPH·,OH·,and O-2· in extracts from different alcohol level Nvzhenzi wine were improved with increasing alcohol level,especially the 40% alcohol Nvzhenzi wine whose EC50 values for DPPH·,OH·,O-2· were 12. 75 mg /m L,62. 86 mg / m L and 15. 93 mg / m L,respectively. Moreover,extraction rates of total flavonoids,luteolin and apigenin in Nvzhenzi wine also were improved with increasing alcohol level. The extraction rates of total flavonoids,luteolin and apigenin in 40% alcohol Nvzhenzi wine were 21. 96 mg / g,40. 07 g / g and 28. 99 g / g respectively,which provided a basis for its health effects.