[1] ZHOU S,HAO T,XU S,et al.Coenzyme A thioester-mediated carbon chain elongation as a paintbrush to draw colorful chemical compounds[J].Biotechnology Advances,2020,43:107 575.
[2] CRAVENS A,PAYNE J,SMOLKE C D.Synthetic biology strategies for microbial biosynthesis of plant natural products[J].Nature Communications,2019,10(1):2 142.
[3] LIAN J,MISHRA S,ZHAO H.Recent advances in metabolic engineering of Saccharomyces cerevisiae:New tools and their applications[J].Metabolic Engineering,2018,50:85-108.
[4] LIN J L,WAGNER J M,ALPER H S.Enabling tools for high-throughput detection of metabolites:Metabolic engineering and directed evolution applications[J].Biotechnology Advances,2017,35(8):950-970.
[5] PANDEY R P,PARAJULI P,KOFFAS M A G,et al.Microbial production of natural and non-natural flavonoids:Pathway engineering,directed evolution and systems/synthetic biology[J].Biotechnology Advances,2016,34(5):634-662.
[6] ZHA J,WU X,GONG G,et al.Pathway enzyme engineering for flavonoid production in recombinant microbes[J].Metabolic Engineering Communications,2019,9:e00104.
[7] DIAO J J,SONG X Y,GUO T H,et al.Cellular engineering strategies toward sustainable omega-3 long chain polyunsaturated fatty acids production:State of the art and perspectives[J].Biotechnology Advances,2020,40:107497.
[8] ZHANG L S,LIANG S,ZONG M H,et al.Microbial synthesis of functional odd-chain fatty acids:A review[J].World Journal of Microbiology & Biotechnology,2020,36(3):35.
[9] LIU N,LIU B,WANG G Y,et al.Lycopene production from glucose,fatty acid and waste cooking oil by metabolically engineered Escherichia coli[J].Biochemical Engineering Journal,2020,155:107 488.
[10] MA Y R,WANG K F,WANG W J,et al.Advances in the metabolic engineering of Yarrowia lipolytica for the production of terpenoids[J].Bioresource Technology,2019,281:449-456.
[11] ZHANG C,HONG K.Production of terpenoids by synthetic biology approaches[J].Frontiers in Bioengineering and Biotechnology,2020,8:347.
[12] CHOI K R,JIAO S,LEE S Y.Metabolic engineering strategies toward production of biofuels[J].Current Opinion in Chemical Biology,2020,59:1-14.
[13] PENG L,FU D,CHU H,et al.Biofuel production from microalgae:A review[J].Environmental Chemistry Letters,2020,18(2):285-297.
[14] SHANMUGAM S,NGO H H,WU Y R.Advanced CRISPR/Cas-based genome editing tools for microbial biofuels production:A review[J].Renewable Energy,2020,149:1 107-1 119.
[15] ZHAO M,HUANG D,ZHANG X,et al.Metabolic engineering of Escherichia coli for producing adipic acid through the reverse adipate-degradation pathway[J].Metabolic Engineering,2018,47:254-262.
[16] ZHAO M,LI G,DENG Y.Engineering Escherichia coli for glutarate production as the C5 platform backbone[J].Applied and Environmental Microbiology,2018,84(16):e00 814-818.
[17] SHEN X L,WANG J,LI C Y,et al.Dynamic gene expression engineering as a tool in pathway engineering[J].Current Opinion in Biotechnology,2019,59:122-129.
[18] XIAO Y,BOWEN C H,LIU D,et al.Exploiting nongenetic cell-to-cell variation for enhanced biosynthesis[J].Nature Chemical Biology,2016,12(5):339.
[19] LIU Y,ZHUANG Y,DING D,et al.Biosensor-based evolution and elucidation of a biosynthetic pathway in Escherichia coli[J].ACS Synthetic Biology,2017,6:837-848.
[20] WANG Q Z,TANG S Y,YANG S.Genetic biosensors for small-molecule products:Design and applications in high-throughput screening[J].Frontiers of Chemical Science and Engineering,2017,11(1):15-26.
[21] MIN B E,HWANG H G,LIM H G,et al.Optimization of industrial microorganisms:Recent advances in synthetic dynamic regulators[J].Journal of Industrial Microbiology & Biotechnology,2017,44(1):89-98.
[22] ZHENG Y,MENG F,ZHU Z,et al.A tight cold-inducible switch built by coupling thermosensitive transcriptional and proteolytic regulatory parts[J].Nucleic Acids Research,2019,47(21):e137.
[23] HARDER B J,BETTENBROCK K,KLAMT S.Temperature-dependent dynamic control of the TCA cycle increases volumetric productivity of itaconic acid production by Escherichia coli[J].Biotechnology and Bioengineering,2018,115(1):156-164.
[24] SUN J,TIAN K,WANG J,et al.Improved ethanol productivity from lignocellulosic hydrolysates by Escherichia coli with regulated glucose utilization[J].Microbial Cell Factories,2018,17(1):66.
[25] YIN X,SHIN H D,LI J,et al.Pgas,a low-pH-induced promoter,as a tool for dynamic control of gene expression for metabolic engineering of Aspergillus niger[J].Applied and Environmental Microbiology,2017,83(6):e03 222-16.
[26] RAJKUMAR A S,LIU G,DAVID B,et al.Engineering of synthetic,stress-responsive yeast promoters[J].Nucleic Acids Research,2016,44(17):e136.
[27] AUSL NDER D,AUSL NDER S,CHARPIN-EL HAMRI G,et al.A synthetic multifunctional mammalian pH sensor and CO2 transgene-control device[J].Molecular Cell,2014,55(3):397-408.
[28] JOHNSON A O,GONZALEZ-VILLANUEVA M,WONG L,et al.Design and application of genetically-encoded malonyl-CoA biosensors for metabolic engineering of microbial cell factories[J].Metabolic Engineering,2017,44:253-264.
[29] XU P,LI L Y,ZHANG F M,et al.Improving fatty acids production by engineering dynamic pathway regulation and metabolic control[J].Proceedings of the National Academy of Sciences of the United States of America,2014,111(31):11 299-11 304.
[30] ZHANG F Z,CAROTHERS J M,KEASLING J D.Design of a dynamic sensor-regulator system for production of chemicals and fuels derived from fatty acids[J].Nature Biotechnology,2012,30(4):354-359.
[31] XU P,WANG W Y,LI L Y,et al.Design and kinetic analysis of a hybrid promoter-regulator system for malonyl-CoA sensing in Escherichia coli[J].ACS Chemical Biology,2014,9(2):451-458.
[32] LIU D,MANNAN A A,HAN Y,et al.Dynamic metabolic control:Towards precision engineering of metabolism[J].Journal of Industrial Microbiology & Biotechnology,2018,45(7):535-543.
[33] DINH C V,PRATHER K L J.Layered and multi-input autonomous dynamic control strategies for metabolic engineering[J].Current Opinion in Biotechnology,2020,65:156-162.
[34] LIU D,EVANS T,ZHANG F.Applications and advances of metabolite biosensors for metabolic engineering[J].Metabolic Engineering,2015,31:35-43.
[35] CHOU H H,KEASLING J D.Programming adaptive control to evolve increased metabolite production[J].Nature Communication,2013,4:2595.
[36] WU J,LIU Y F,ZHAO S,et al.Application of dynamic regulation to increase L-phenylalanine production in Escherichia coli[J].Journal of Microbiology and Biotechnology,2019,29(6):923-932.
[37] KR MER R.Systems and mechanisms of amino acid uptake and excretion in prokaryotes[J].Archives of Microbiology,1994,162(1):1-13.
[38] HALPERN Y S.Genetics of amino acid transport in bacteria[J].Annual Review of Genetics,1974,8(1):103-133.
[39] YAZAKI K.Transporters of secondary metabolites[J].Current Opinion in Plant Biology,2005,8(3):301-307.
[40] BURNS B P,MENDZ G L.‘Metabolite Transport',in Helicobacter pylori:Physiology and genetics[M].Washington (DC):ASM Press,2001.
[41] MINAGAWA S,INAMI H,KATO T,et al.RND type efflux pump system MexAB-OprM of pseudomonas aeruginosa selects bacterial languages,3-oxo-acyl-homoserine lactones,for cell-to-cell communication[J].BMC Microbiology,2012,12:70.
[42] PEARSON J P,VAN DELDEN C,IGLEWSKI B H.Active efflux and diffusion are involved in transport of Pseudomonas aeruginosa cell-to-cell signals[J].Journal of Bacteriology,1999,181(4):1 203-1 210.
[43] PRESCOTT R D,DECHO A W.Flexibility and adaptability of quorum sensing in nature[J].Trends in Microbiology,2020,28(6):436-444.
[44] SCHUSTER M,SEXTON D J,DIGGLE S P,et al.Acyl-homoserine lactone quorum sensing:From evolution to application[J].Annual Review of Microbiology,2013,67(1):43-63.
[45] KIM E M,MIN WOO H,TIAN T,et al.Autonomous control of metabolic state by a quorum sensing (QS)-mediated regulator for bisabolene production in engineered E.coli[J].Metabolic Engineering,2017,44:325-336.
[46] DINH C V,PRATHER K L.Development of an autonomous and bifunctional quorum-sensing circuit for metabolic flux control in engineered Escherichia coli[J].Proceedings of the National Academy of Sciences of the United States of America,2019,116(51):25 562-25 568.
[47] YANG Y,LIN Y,WANG J,et al.Sensor-regulator and RNAi based bifunctional dynamic control network for engineered microbial synthesis[J].Nature Communications,2018,9(1):3 043.
[48] LO T M,CHNG S H,TEO W S,et al.A two-layer gene circuit for decoupling cell growth from metabolite production[J].Cell Systems,2016,3(2):133-143.
[49] MOSER F,BORUJENI A E,GHODASARA A N,et al.Dynamic control of endogenous metabolism with combinatorial logic circuits[J].Molecular Systems Biology,2018,14(11):e8605.
[50] GUPTA A,REIZMAN I M,REISCH C R,et al.Dynamic regulation of metabolic flux in engineered bacteria using a pathway-independent quorum-sensing circuit[J].Nature Biotechnology,2017,35(3):273-279.
[51] DOONG S J,GUPTA A,PRATHER K L.Layered dynamic regulation for improving metabolic pathway productivity in Escherichia coli[J].Proceedings of the National Academy of Sciences of the United States of America,2018,115(12):2 964-2 969.
[52] KAMINSKI T S,SCHELER O,GARSTECKI P.Droplet microfluidics for microbiology:Techniques,applications and challenges[J].Lab on a Chip,2016,16(12):2 168-2 187.
[53] BOWMAN E K,ALPER H S.Microdroplet-assisted screening of biomolecule production for metabolic engineering applications[J].Trends in Biotechnology,2020,38(7):701-714.
