A compoundMomordica charantia andCyclocarya paliurus tea (compound tea) was found to not only inhibit the accumulation of reactive oxygen species and age pigments and improve neuroprotection,but also alleviate fat accumulation in previous study.The model of Caenorhabditis elegans was used to further study its antioxidative stress activity,which provided a theoretical basis for further promotion and application.First,it provided the protection toC.elegans exposed to H2O2-and paraquat-induced oxidative stress,especially in the mutant TK22 sensitive to oxidative stress.Further exploration of its antioxidant properties revealed that the antioxidant defense system ofC.elegans was significantly activated by compound tea.In addition,the expression of antioxidant enzyme genes (sod-3,sod-5,ctl-1,andctl-2) and stress resistance genes (hsp-16.1 andhsp-16.2) were also significantly increased.Finally,it was found that y did not damage the reproduction and development ofC.elegans,and even alleviated the decline of mobility.Overall,these results provided promising data for compound tea as a dietary adjuvant in oxidative stress management,and added value toMomordica charantia andCyclocarya paliurus by seeking new and innovative applications.
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