Food and Fermentation Industries >

2021 , Vol. 47 >Issue 7: 123 - 129

DOI: https://doi.org/10.13995/j.cnki.11-1802/ts.025860

Study on the effect of extracts of E planting No.8 and Picual olive leaves on lowering blood lipid in hyperlipidemia mice

  • WANG Zhongming ,
  • XIE Yuejie ,
  • LI Yonghong ,
  • WEI Huaheng ,
  • XING Qiao ,
  • CHEN Cong ,
  • CHENG Xinxian ,
  • WANG Qiang
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  • 1(College of Biological and Chemical Engineering,Chongqing University of Education,Chongqing 400067,China)
    2(Cooperative Innovation Center of Lipid Resources and Children’s Daily Chemicals,Chongqing University of Education,Chongqing 400067,China)

Received date: 2020-10-14

  Revised date: 2020-11-03

  Online published: 2021-05-20

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Abstract

The purpose of this study is to investigate the intervention effect of Picual olive leaves (POL) and E planting No.8 olive leaves (EP8OL) extracts on body weight, liver damage and lipid reduction in hyperlipidemia mice, so as to provide data for the development of functional olive leave extract products.The hyperlipidemia mice model was established by feeding with a high-fat diet and the mice were divided into four groups, including blank group, control group, low-dose group, medium-dose group and high-dose group.The indexes were measured after four weeks of gavage.Compared with the control group, the results showed that the hyperlipidemia mice after 28 days’ gavage significantly reduced their body weight, relieve liver damage and the levels of triglyceride (TG), total cholesterol (TCHO) and low-density lipoprotein cholesterol (LDL-C) in serum declined.Meanwhile, the high-density lipoprotein cholesterol (HDL-C) level in serum was raised.The results showed that both the POL and EP8OL extracts could effectively reduced the body weight and relieve liver damage, improved lipid metabolism disorder and reduced the level of blood lipid for the hyperlipidemia mice.In addition, there was little difference between the two kinds of olive leave extracts.They were potential natural activity products to improve hyperlipidemia.Therefore, the research of POL and EP8OL extract shows the very important significance and the exploration value is also important in the area of health care.

Key words： E planting No.8; Picual; olive leaves; hyperlipidemia mice; hypolipidemic

Cite this article

WANG Zhongming , XIE Yuejie , LI Yonghong , WEI Huaheng , XING Qiao , CHEN Cong , CHENG Xinxian , WANG Qiang . Study on the effect of extracts of E planting No.8 and Picual olive leaves on lowering blood lipid in hyperlipidemia mice[J]. Food and Fermentation Industries, 2021 , 47(7) : 123 -129 . DOI: 10.13995/j.cnki.11-1802/ts.025860

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