Preparation of histamine surface molecularly imprinted polymer and its application in yoghurt

  • LI Xinpei ,
  • WANG Xiujun ,
  • XU Fei ,
  • CAO Hui ,
  • YUAN Min ,
  • YU Dongwei ,
  • LIU Zhenmin
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  • 1(School of Medical Instruments and Food Engineering,Shanghai Engineering Research Center for Food Rapid Detection,University of Shanghai for Science and Technology,Shanghai 200093,China)
    2(Shandong Gold Mining Co.Ltd.,Jinan 250014,China)
    3(Inner Mongolia MengNiu Dairy Products Co.Ltd,Hohhot 011500,China)
    4(Dairy Research Institute,Bright Dairy and Food Co.Ltd.,Shanghai 200436,China)

Received date: 2020-11-12

  Revised date: 2021-02-03

  Online published: 2021-07-16

Abstract

Histamine usually exists in fermented food. However, it may cause serious allergic reaction if people intake food with high content of histamine. Therefore, it is necessary to establish a method for the adsorption and removal of histamine in food. In this study, a histamine molecularly imprinted polymer (MIP) on silica surface was prepared by surface polymerization. Histamine was used as the template molecule, methacrylic acid as functional monomer, and ethylene glycol dimethacrylate as crosslinker with a ratio of 1∶10∶40. The property of prepared polymers was characterized by adsorption kinetics and isothermal adsorption experiment. The results showed that the prepared MIP had good adsorption to histamine with a highest adsorption capacity of 13.1 mg/g, and the imprint factor reached 4. The prepared MIP also had an excellent specific adsorption to histamine in comparison with histidine, tyramine and phenylethylamine. The imprinted polymer was successfully applied to adsorb and remove histamine in yoghurt.

Cite this article

LI Xinpei , WANG Xiujun , XU Fei , CAO Hui , YUAN Min , YU Dongwei , LIU Zhenmin . Preparation of histamine surface molecularly imprinted polymer and its application in yoghurt[J]. Food and Fermentation Industries, 2021 , 47(11) : 1 -7 . DOI: 10.13995/j.cnki.11-1802/ts.026159

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