Food and Fermentation Industries >

2021 , Vol. 47 >Issue 11: 295 - 302

DOI: https://doi.org/10.13995/j.cnki.11-1802/ts.025579

Research progress in biotransformation of plant lignans

  • FENG Chengcheng ,
  • ZHANG Wen ,
  • CAI Zizhe ,
  • LI Ying ,
  • WANG Yong ,
  • ZHANG Ning
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  • 1(Department of Food Science and Engineering,Jinan University,Guangzhou 510632,China)
    2(Jinan University-Saskatchewan Oilseed Joint Laboratory,Guangzhou 510632,China)
    3(School of Nursing,Yichun Vocational and Technical College,Yichun 336000,China)

Received date: 2020-09-09

  Revised date: 2020-10-27

  Online published: 2021-07-16

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Abstract

Phytoestrogens are weak oestrogens found in plants or derived from plant precursors.They are structurally similar to endogenous oestrogens which can have both oestrogenic and anti-oestrogenic effects.Lignans are phytoestrogens found in seeds such as flaxseeds,vegetables,fruits,beverages,and other daily foods.Dietary lignans and their derived metabolites have antioxidant,anti-malignant cell proliferation,estrogen-like properties and other functions,and can prevent breast and prostate cancer,cardiovascular diseases and diabetes.Due to their low bioavailability,dietary lignans must be converted into enterolignans such as enterodiol (END) and enterolactone (ENL) to exert their beneficial effects.The conversion of dietary lignans results from the activities of both dominant and subdominant anaerobic bacterial communities in the human intestinal tract.Therefore,the bioavailability of dietary lignans can be improved by transforming them in vitro.Biotransformation is a much more economical,efficient and environmentally friendly method of mass production of enterolignans from dietary lignans than chemical synthesis.The structure,species and distribution of lignans were briefly described,and the intestinal microbial metabolism mechanism of lignans were discussed,as well as the research progress of microbial and enzymatic transformation of lignans in vitro were reviewed.

Key words： phytoestrogen; lignans; biotransformation; enterodiol; enterolactone

Cite this article

FENG Chengcheng , ZHANG Wen , CAI Zizhe , LI Ying , WANG Yong , ZHANG Ning . Research progress in biotransformation of plant lignans[J]. Food and Fermentation Industries, 2021 , 47(11) : 295 -302 . DOI: 10.13995/j.cnki.11-1802/ts.025579

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