Protective effect of different dandelion extracts on alcoholic liver injury

  • XIA Jin ,
  • CHEN Yilun
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  • (College of Food Science and Engineering, Shandong Agricultural University, Taian 271018, China)

Received date: 2020-10-21

  Revised date: 2020-12-11

  Online published: 2021-08-20

Abstract

The effects of dandelion water extract and alcohol extract on alcohol-induced liver injury related indicators (glutamic oxaloacetic transaminase, glutamic pyruvic transaminase, triglyceride, malondialdehyde, superoxide dismutase, glutathione) were studied by animal and cell experiments. Then the antioxidant properties of water and alcohol extract of dandelion were determined in vitro and in vivo, and the liver-protecting mechanism of dandelion extract was explored. The results showed that both water extract and alcohol extract of dandelion had protective effect on alcoholic liver injury. Compared with alcohol extract, the water extract had lower action dose, and could effectively reduce the content of glutathione transaminase in serum and glutathione in liver, and better protect the mitochondria of hepatocytes. The antioxidant properties and correlation analysis showed that the liver protective effect of the dandelion extract was closely related to its antioxidant effect.

Cite this article

XIA Jin , CHEN Yilun . Protective effect of different dandelion extracts on alcoholic liver injury[J]. Food and Fermentation Industries, 2021 , 47(14) : 94 -99 . DOI: 10.13995/j.cnki.11-1802/ts.025923

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