Food and Fermentation Industries >

2021 , Vol. 47 >Issue 18: 46 - 53

DOI: https://doi.org/10.13995/j.cnki.11-1802/ts.026388

Migration of three antioxidants from PET/LDPE composite film to fatty food simulant and estimation of their diffusion coefficient

  • LYU Xiaomin ,
  • CAI Xiangyu ,
  • CHEN Lu ,
  • CHENG Juan ,
  • HU Changying ,
  • WANG Zhiwei ,
  • WU Yujie
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  • 1(Key Laboratory of Product Packaging and Logistics of Guangdong Higher Education Institutes, College of packaging engineering, Jinan University, Zhuhai 519070, China)
    2(Nanning Customs Technical Center, Nanning 530021,China)
    3(Department of Food Science and Engineering, Jinan University, Guangzhou 510632,China)
    4(Chinese Academy of Inspection and Quarantine, Beijing 100176,China)

Received date: 2020-12-07

  Revised date: 2021-01-15

  Online published: 2021-10-18

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Abstract

An analytical method was established for detecting three antioxidants (Irganox1076, Irgafos168 and 2,4-di-tert-butylphenol) in PET/LDPE composite film using liquid chromatography-triple quadrupole tandem mass spectrometry (LC-MS/MS). The migration behavior of three antioxidants in PET/LDPE composite film to isooctane and 95% ethanol was studied and Crank model was used to calculates the migration diffusion coefficient. The results showed that the detection limits of the three antioxidants detected by LC/MS-MS were all 0.2 μg/L, and the quantification limits were all less than or equal to 0.8 μg/L. The linearity was good in the concentration range of 5-240 μg/L with the correlation coefficients greater than 0.998. The migration amount of three antioxidants increased with increasing temperature and time until reaching migration equilibrium at 20-70 ℃. And the higher the temperature was, the faster the equilibrium state would be reached. The Crank model fitted the migration experimental data well, and the relationship between the migration diffusion coefficients of three antioxidants and the temperature conformed to the Arrhenius formula. Under the conditions of 70 ℃ for 2 hours and 40 ℃ for 72 hours, the migration ratio of three antioxidants from LDPE film and PET/LDPE composite film to two food simulants were not significantly different (P>0.05). It was indicated that the PET film had no significant effect on the migration of the three antioxidants in the LDPE film under specific migration conditions.

Key words： liquid chromatography-triple quadrupole tandem mass spectrometry; PET/LDPE composite film; antioxidants; migration; diffusion coefficient

Cite this article

LYU Xiaomin , CAI Xiangyu , CHEN Lu , CHENG Juan , HU Changying , WANG Zhiwei , WU Yujie . Migration of three antioxidants from PET/LDPE composite film to fatty food simulant and estimation of their diffusion coefficient[J]. Food and Fermentation Industries, 2021 , 47(18) : 46 -53 . DOI: 10.13995/j.cnki.11-1802/ts.026388

References

[1] TORRES A, GUARDA A, MORAGA N, et al.Experimental and theoretical study of thermodynamics and transport properties of multilayer polymeric food packaging[J].European Food Research & Technology, 2012, 234(4):713-722.
[2] GREEN S,BAI S, CHEATHAM M, et al.Determination of antioxidants in polyolefins using total dissolution methodology followed by RPLC[J].Journal of Separation Science, 2010,33(22):3 455-3 462.
[3] YAN Y, HU C Y, WANG Z W, et al.Degradation of Irgafos 168 and migration of its degradation products from PP-R composite films[J].Packaging Technology and Science, 2018,31(10):679-688.
[4] 马少波, 郑亚兰, 吴晓妮, 等.塑料抗氧剂的研究和发展趋势[J].塑料科技, 2015,43(1):100-103.
MA S B, ZHENG Y L, WU X N, et al.Study and development trend of plastic antioxidants[J].Plastics Science and Technology, 2015,43(1):100-103.
[5] DOPICO-GARCÍA M S, LÓPEZ-VILARIÑÓ J M, GONZÁLEZ-RODRÍGUEZ M V.Antioxidant content of and migration from commercial polyethylene, polypropylene, and polyvinyl chloride packages[J].Journal of Agricultural and Food Chemistry, 2007, 55(8):3 225-3 231.
[6] 刘志刚, 王志伟.塑料包装材料化学物向食品迁移的模型研究进展[J].高分子材料科学与工程, 2007, 23(5):19-23.
LIU Z G, WANG Z W.Study on mathematical model for predicting migration of chemical substances from plastic packaging materials[J].Polymer Materials Science & Engineering, 2007,23 (5):19-23.
[7] VARSHA K K, DEVENDRA L, SHILPA G, et al.2,4-Di-tert-butyl phenol as the antifungal, antioxidant bioactive purified from a newly isolated Lactococcus sp.[J].International Journal of Food Microbiology, 2015, 211:44-50.
[8] CHOI S J, KIM J K, KIM H K, et al.2,4-Di-tert-butylphenol from sweet potato protects against oxidative stress in PC12 cells and in mice[J].Journal of Medicinal Food, 2013,16(11):977-983.
[9] YANG Y P, HU C Y, ZHONG H N, et al.Effects of ultraviolet (UV) on degradation of irgafos 168 and migration of its degradation products from polypropylene films[J].Journal of Agricultural and Food Chemistry, 2016,64(41):7 866-7 873.
[10] BHUNIA K,SABLANI S S, YANG J M, et al.Migration of chemical compounds from packaging polymers during microwave, conventional heat treatment, and storage[J].Comprehensive Reviews in Food Science and Food Safety, 2013,12(5):523-545.
[11] 熊中强, 王利兵, 李宁涛, 等.气相色谱法测定高分子食品包装材料中抗氧化剂的残留量[J].色谱, 2011,29(3):273-276.
XIONG Z Q, WANG L B, LI N T, et al.Determination of antioxidant residues in polymer food package using.gas chromatography[J].Chinese Journal of Chromatography, 2011, 29(3):273-276.
[12] 国家质量监督检验检疫总局. SN/T 3042—2011 出口食品接触材料 高分子材料中抗氧化剂的测定 气相色谱法[S].北京:中国标准出版社, 2012.
General Administration of Quality Supervision, Inspection and Quarantine of the People′s Republic of China.SN/T 3042—2011 Food contact materials for export-Determination of antioxidants in polymers-Gas chromatography[S].Beijing:China Standard Press, 2011.
[13] 姚帮本, 王道俊, 储大勇.固相萃取-气相色谱-串联质谱法测定塑料食品包装材料中3种抗氧化剂的残留量[J].化学分析计量, 2014,23(6):20-24.
YAO B B, WANG D J, CHU D Y, Determination of three antioxidant residues in food plastic packaging materials by solid phase extraction-gas chromatography tandem mass spectrometry[J].Chemical Analysis and Meterage, 2014, 23(6):20-24.
[14] 杨岳平, 胡长鹰, 钟怀宁, 等.抗氧剂168的降解及其降解产物的测定[J].现代食品科技, 2016,32(6):304-309.
YANG Y P, HU C Y, ZHONG H N, et al.Degradation of Irgafos 168 and determination of its degradation products[J].Modern Food Science Technology, 2016, 32(6):304-309.
[15] LIN Q B, LI B, SONG H, et al.Determination of 7 antioxidants, 8 ultraviolet absorbents, and 2 fire retardants in plastic food package by ultrasonic extraction and ultra performance liquid chromatography[J].Journal of Liquid Chromatography & Related Technologies, 2011, 34(9):730-743.
[16] 薄艳娜, 林勤保, 吴恩玉, 等.纳米银-聚乙烯复合膜中4种添加剂的检测[J].包装学报, 2017, 9(2):1-5;24.
BO Y N, LIN Q B, WU E Y, et al.Determination of four additives in nano silver polyethylene composite film[J].Packaging Journal, 2017,9(2):1-5;24.
[17] LI B, WANG Z W, LIN Q B, et al.Simultaneous determination of antioxidants and ultraviolet stabilizers in polypropylene food packaging and food simulants by high-performance liquid chromatography[J].Acta Chromatographica, 2017,29(2):173-192.
[18] 张宁, 王彦, 王薇薇,等.高效液相色谱三重四级杆质谱联用法同时测定食品接触材料中12种塑化剂和抗氧化剂[J].现代生物医学进展, 2018, 18(14):2 623-2 630;2 622.
ZHANG N, WANG Y, WANG W W, et al.Simultaneous determination of plasticizers and antioxidants in food contact materials by high performance liquid chromatography/triple quadrupole mass spectrometry[J].Progress in Modern Biomedicine, 2018, 18(14):2 623-2 630;2 622.
[19] CHANG Y, KANG K, PARK S J, et al.Experimental and theoretical study of polypropylene:Antioxidant migration with different food simulants and temperatures[J].Journal of Food Engineering, 2019,244:142-149.
[20] GALOTTO M J, TORRES A, GUARDA A, et al.Experimental and theoretical study of LDPE versus different concentrations of irganox 1076 and different thickness[J].Food Research International, 2011,44(2):566-574.
[21] 徐雨军. 食品聚乙烯包装材料中酚类化合物的测定及迁移研究[D].扬州:扬州大学,2016.
XU Y J.Determination and migration of phenolic compounds in polyethylene packaging materials[D].Yangzhou:Yangzhou University, 2016.
[22] YOO S, SIGUA G, MIN D, et al.The influence of high-pressure processing on the migration of irganox 1076 from polyethylene films[J].Packaging Technology and Science, 2014,27(4):255-263.
[23] KANG K, CHANG Y, CHOI J C, et al.Migration study of butylated hydroxytoluene and irganox 1010 from polypropylene treated with severe processing conditions[J].Journal of Food science, 2018,83(4):1 005-1 010.
[24] 单利君, 林勤保, 韩善辉, 等.纳米银—聚乙烯复合包装中银对2种抗氧化剂向食品模拟物迁移的影响[J].食品科学, 2016, 37(12):182-186.
SHAN L J, LIN Q B, HAN S H, et al.Impact of nanosilver on migration of two antioxidants from nanosilver-plastic food packaging to food simulants [J].Food Science, 2016,37(12):182-186.
[25] ALIN J, HAKKARAINEN M.Microwave heating causes rapid degradation of antioxidants in polypropylene packaging, leading to greatly increased specific migration to food simulants as shown by ESI-MS and GC-MS[J].Journal of Agricultural and Food Chemistry, 2011, 59(10):5 418-5 427.
[26] BELDì G, PASTORELLI S, FRANCHINI F, et al.Time-and temperature-dependent migration studies of irganox 1076 from plastics into foods and food simulants[J].Food Additives & Contaminants:Part A, 2012, 29(5):836-845.
[27] 中华人民共和国国家卫生和计划生育委员会. GB 31604.1—2015食品安全国家标准 食品接触材料及制品迁移试验通则[S].北京:中国标准出版社, 2016.
National Health and Family Planning Commission.GB 31604.1—2015 National Food Safety Standard Migration test rules for food contact materials and products[S].Beijing:China Standard Press, 2015.
[28] CRANK J.The Mathematics of Diffusion[M].2nd ed.New York:Oxford University Press, 1975.
[29] GARDE J A, CATALÁ R, GAVARA R, et al.Characterizing the migration of antioxidants from polypropylene into fatty food simulants[J].Food Additives & Contaminants, 2001, 18(8):750-762.
[30] MAITI M, BHOWMICK A K.Effect of polymer-clay interaction on solvent transport behavior of fluoroelastomer–clay nanocomposites and prediction of aspect ratio of nanoclay[J].Journal of Applied Polymer Science, 2007, 105(2):435-445.
[31] HANSEN C M.Hansen Solubility Parameters:A User′s Handbook[M].New York:CRC Press, 2007.
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