Ameliorating effects of Auricularia auricula on obesity and gut microbiota dysbiosis in mice induced by high fat diet

  • ZHU Lina ,
  • HU Jinhong ,
  • ZHANG Ting ,
  • YUE Tianli ,
  • SONG Wei
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  • 1(College of Food Science and Technology, Northwest University, Xi’an 710069, China)
    2(Laboratory of Nutritional and Healthy Food-Individuation Manufacturing Engineering, Xi’an 710069, China)
    3(Research Center of Food Safety Risk Assessment and Control, Xi’an 710069, China)

Received date: 2021-06-21

  Revised date: 2021-07-09

  Online published: 2021-11-30

Abstract

Auricularia auricula was added into the high-fat diets (HFD) of mice to ameliorate fat and gut microbiota dysbiosis. The experiment was carried out for four weeks and the mice were weighed on alternate day. Feces were collected for high-throughput sequencing in the last week. After executed, the serum, liver and spleen were collected for determination. The results showed that dietary supplementation of A. auricula significantly reduced the body weight, the content of cholesterol and triglyceride and the content of lipid droplets in liver. Moreover, daily intake of A. auricula effectively alleviated the disturbance of gut microbiota caused by HFD. In conclusion, dietary supplementation of A. auricula effectively ameliorated the obesity, hepatic lipid accumulation and gut microbiota dysbiosis of mice.

Cite this article

ZHU Lina , HU Jinhong , ZHANG Ting , YUE Tianli , SONG Wei . Ameliorating effects of Auricularia auricula on obesity and gut microbiota dysbiosis in mice induced by high fat diet[J]. Food and Fermentation Industries, 2021 , 47(21) : 94 -101 . DOI: 10.13995/j.cnki.11-1802/ts.028429

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