Encapsulation strategies of ferritin and its application for food bioactive compounds delivery: A review

  • CHEN Hai ,
  • MA Liang ,
  • DAI Hongjie ,
  • FU Yu ,
  • WANG Hongxia ,
  • ZHANG Yuhao
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  • (College of Food Science,Southwest University,Chongqing 400715,China)

Received date: 2021-04-25

  Revised date: 2021-05-26

  Online published: 2022-03-04

Abstract

Ferritin is a multi-subunit protein nanocage that is widely distributed in many types of organisms from microbes to plants and animals. Its function mainly involves the regulation of iron metabolism, as well as cell protection from oxidative damage caused by various environmental stresses. In recent years, with a deep understanding of ferritin protein, it has been considered as a novel protein nano-carrier that can be applied in multiple disciplines due to the unique cage-like structure and specific characteristics of ferritin nanocage. Herein, the distribution, structure, function and preparation of ferritin nanocage have been introduced and followed by an overview of the molecular encapsulation strategy of ferritin nanocages, including the reversible disassembly/reassembly property mediated approach and stimulus-responsive channel-mediated approach. Finally, the applications of ferritin as a nano-carrier for food bioactive compounds encapsulation were reviewed. The purpose of this review was to provide research ideas for the preparation and development of ferritin nano-carrier and its application in food science.

Cite this article

CHEN Hai , MA Liang , DAI Hongjie , FU Yu , WANG Hongxia , ZHANG Yuhao . Encapsulation strategies of ferritin and its application for food bioactive compounds delivery: A review[J]. Food and Fermentation Industries, 2022 , 48(3) : 304 -310 . DOI: 10.13995/j.cnki.11-1802/ts.027868

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