Progress of synthesis methods, structural characteristics and biological activities of zinc polysaccharides

  • YUAN Xintian ,
  • CHEN Huaguo ,
  • ZHAO Chao ,
  • GONG Xiaojian ,
  • ZHOU Xin
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  • 1(Guizhou University of Traditional Chinese Medicine, Guiyang 550002, China)
    2(Key Laboratory for Information System of Mountainous Areas and Protection of Ecological Environment, Guizhou Normal University, Guiyang 550001, China)
    3(Guizhou Engineering Laboratory for Quality Control & Evaluation Technology of Medicine, Guizhou Normal University, Guiyang 550001, China)

Received date: 2021-09-27

  Revised date: 2021-10-19

  Online published: 2022-08-19

Abstract

Zinc is one of the essential trace elements for human health. It is also an important component of more than 300 enzymes, which plays an important role in physiological processes such as protein and DNA synthesis, cell growth and proliferation, and metabolic regulation. Moreover, zinc polysaccharide is a complex of polysaccharides chelated with soluble zinc salt, which has the characteristics of high bioavailability, low toxicity, easy digestion and absorption. Zinc polysaccharides could be used as a novel zinc supplementation due to its characteristics including antioxidant, hypoglycemic, anti-inflammatory, anti-cancer, immunomodulation, antibacterial and hepatoprotective compared with polysaccharides and inorganic zinc. This article briefly describes the synthesis methods, structural characterization methods and biological activities of zinc polysaccharides. Then, the problems such as large differences in zinc content in different zinc polysaccharides, complex structure, limitation of biological activity studies and lack of clinical experimental datawere pointed out. This article could provide an outlook on the application of zinc polysaccharides.

Cite this article

YUAN Xintian , CHEN Huaguo , ZHAO Chao , GONG Xiaojian , ZHOU Xin . Progress of synthesis methods, structural characteristics and biological activities of zinc polysaccharides[J]. Food and Fermentation Industries, 2022 , 48(14) : 336 -344 . DOI: 10.13995/j.cnki.11-1802/ts.029527

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