Food and Fermentation Industries >

2022 , Vol. 48 >Issue 17: 298 - 303

DOI: https://doi.org/10.13995/j.cnki.11-1802/ts.030769

Progress in the two-component signal transduction system of yogurt starter

  • LU Yinyue ,
  • SONG Xin ,
  • XIA Yongjun ,
  • WANG Guangqiang ,
  • AI Lianzhong ,
  • XIONG Zhiqiang
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  • (Shanghai Engineering Research Center of Food Microbiology, School of Health Science and Engineering, University of Shanghai for Science and Technology, Shanghai, 200093, China)

Received date: 2022-01-10

  Revised date: 2022-01-20

  Online published: 2022-10-01

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Abstract

Yogurt starter is a microbial material composed of lactic acid bacteria (LAB), mainly Lactobacillus delbrueckii subsp. bulgaricus and Streptococcus thermophilus. The two-component signal transduction system (TCS) composed of the transmembrane receptor histidine protein kinase and the homologous intracytoplasmic response regulator protein is a common signal mechanism in bacteria, which enables bacteria to sense external stimuli and regulate their own physiological and biochemical processes. Compared with the model bacteria such as Escherichia coli, Bacillus subtilis, and Streptomyces coelicolor, the response and regulation mechanism of LAB TCS is lack of systematic elucidation. This article summarizes the progress in the TCS of L. delbrueckii subsp. bulgaricus and S. thermophilus, with a view to provide help for the research of LAB TCSs and the industrial production control of yogurt.

Key words： yogurt starter; lactic acid bacteria; two-component signal transduction system; Lactobacillus delbrueckii subsp. bulgaricus; Streptococcus thermophilus

Cite this article

LU Yinyue , SONG Xin , XIA Yongjun , WANG Guangqiang , AI Lianzhong , XIONG Zhiqiang . Progress in the two-component signal transduction system of yogurt starter[J]. Food and Fermentation Industries, 2022 , 48(17) : 298 -303 . DOI: 10.13995/j.cnki.11-1802/ts.030769

References

[1] MASOOD M I, QADIR M I, SHIRAZI J H, et al.Beneficial effects of lactic acid bacteria on human beings[J].Critical Reviews in Microbiology, 2011, 37(1):91-98.
[2] MOKOENA M P, MUTANDA T, OLANIRAN A O.Perspectives on the probiotic potential of lactic acid bacteria from African traditional fermented foods and beverages[J].Food & Nutrition Research, 2016, 60:29630.
[3] 苏敦, 任发政, 刘松玲, 等.菌株发酵特性研究及复合酸奶发酵剂的筛选[J].中国奶牛, 2017(9):50-57.
SU D, REN F Z, LIU S L, et al.Study of bacterial strains fermentation characteristics and development of yoghurt starter[J].China Dairy Cattle, 2017(9):50-57.
[4] 杜心恬, 宋馨, 刘欣欣, 等.细菌胞外多糖生物合成转录调控因子研究进展[J].微生物学通报, 2021, 48(2):573-581.
DU X T, SONG X, LIU X X, et al.Advances in transcription regulators of bacterial exopolysaccharides biosynthesis[J].Microbiology China, 2021, 48(2):573-581.
[5] ZHANG D F, YE J Z, DAI H H, et al.Identification of ethanol tolerant outer membrane proteome reveals OmpC-dependent mechanism in a manner of EnvZ/OmpR regulation in Escherichia coli [J].Journal of Proteomics, 2018, 179:92-99.
[6] ZHENG C K, LI L Z, GE H J, et al.Role of two-component regulatory systems in the virulence of Streptococcus suis[J].Microbiological Research, 2018, 214:123-128.
[7] YUAN J, JIN F, GLATTER T, et al.Osmosensing by the bacterial PhoQ/PhoP two-component system[J].Proceedings of the National Academy of Sciences of the United States of America, 2017, 114(50):E10792-E10798.
[8] VAN DE GUCHTE M, PENAUD S, GRIMALDI C, et al.The complete genome sequence of Lactobacillus bulgaricus reveals extensive and ongoing reductive evolution[J].Proceedings of the National Academy of Sciences of the United States of America, 2006, 103(24):9 274-9 279.
[9] MAKAROVA K, SLESAREV A, WOLF Y, et al.Comparative genomics of the lactic acid bacteria[J].Proceedings of the National Academy of Sciences of the United States of America, 2006, 103(42):15 611-15 616.
[10] WANG C, CUI Y H, QU X J.Identification of proteins regulated by acid adaptation related two component system HPK1/RR1 in Lactobacillus delbrueckii subsp.bulgaricus[J].Archives of Microbiology, 2018, 200(9):1 381-1 393.
[11] CUI Y H, LIU W, QU X J, et al.A two component system is involved in acid adaptation of Lactobacillus delbrueckii subsp.bulgaricus[J].Microbiological Research, 2012, 167(5):253-261.
[12] 宋雪梅, 张炎, 张卫兵, 等.成熟温度对牦牛乳硬质干酪中乳酸菌自溶及氨肽酶活性的影响[J].食品与发酵工业, 2016, 42(5):38-43.
SONG X M, ZHANG Y, ZHANG W B, et al.Effect of ripening temperature on the autolysis and aminopeptidase activity of Lactococcus lactis in hard cheese from yak milk[J].Food and Fermentation Industries, 2016, 42(5):38-43.
[13] PANG X Y, CUI W M, LIU L, et al.Gene knockout and overexpression analysis revealed the role of N-acetylmuramidase in autolysis of Lactobacillus delbrueckii subsp.bulgaricus ljj-6[J].PLoS One, 2014, 9(8):e104829.
[14] PANG X Y, ZHANG S W, LU J, et al.Identification and functional validation of autolysis-associated genes in Lactobacillus bulgaricus ATCC BAA-365[J].Frontiers in Microbiology, 2017, 8:1367.
[15] PANG X Y, LIU C P, LYU P C, et al.Identification of quorum sensing signal molecule of Lactobacillus delbrueckii subsp.bulgaricus[J].Journal of Agricultural and Food Chemistry, 2016, 64(49):9 421-9 427.
[16] BOLOTIN A, QUINQUIS B, RENAULT P, et al.Complete sequence and comparative genome analysis of the dairy bacterium Streptococcus thermophilus[J].Nature Biotechnology, 2004, 22(12):1 554-1 558.
[17] XIONG Z Q, KONG L H, MENG H L, et al.Comparison of gal-lac operons in wild-type galactose-positive and-negative Streptococcus thermophilus by genomics and transcription analysis[J].Journal of Industrial Microbiology and Biotechnology, 2019, 46(5):751-758.
[18] XIONG Z Q, KONG L H, LAI P F H, et al.Genomic and phenotypic analyses of exopolysaccharide biosynthesis in Streptococcus thermophilus S-3[J].Journal of Dairy Science, 2019, 102(6):4 925-4 934.
[19] 潘晖, 刘欣欣, 孔令慧, 等.精氨酸代谢调控蛋白ArgR调控嗜热链球菌胞外多糖合成[J].微生物学报, 2020, 60(11):2 412-2 422.
PAN H, LIU X X, KONG L H, et al.Arginine regulator ArgR regulates exopolysaccharides biosynthesis of Streptococcus thermophilus[J].Acta Microbiologica Sinica, 2020, 60(11):2 412-2 422.
[20] HOLS P, HANCY F, FONTAINE L, et al.New insights in the molecular biology and physiology of Streptococcus thermophilus revealed by comparative genomics[J].FEMS Microbiology Reviews, 2005, 29(3):435-463.
[21] MENDE S, ROHM H, JAROS D.Influence of exopolysaccharides on the structure, texture, stability and sensory properties of yoghurt and related products[J].International Dairy Journal, 2016, 52:57-71.
[22] HU T, ZHANG Y S, CUI Y H, et al.Technological properties assessment and two component systems distribution of Streptococcus thermophilus strains isolated from fermented milk[J].Archives of Microbiology, 2018, 200(4):567-580.
[23] CLEVELAND J, MONTVILLE T J, NES I F, et al.Bacteriocins:safe, natural antimicrobials for food preservation[J].International Journal of Food Microbiology, 2001, 71(1):1-20.
[24] FONTAINE L, BOUTRY C, GUÉDON E, et al.Quorum-sensing regulation of the production of blp bacteriocins in Streptococcus thermophilus[J].Journal of Bacteriology, 2007, 189(20):7 195-7 205.
[25] FONTAINE L, HOLS P.The inhibitory spectrum of thermophilin 9 from Streptococcus thermophilus LMD-9 depends on the production of multiple peptides and the activity of BlpG(St), a thiol-disulfide oxidase[J].Applied and Environmental Microbiology, 2008, 74(4):1 102-1 110.
[26] WANG D, WANG Q, QIU Y M, et al.Untangling the transcription regulatory network of the bacitracin synthase operon in Bacillus licheniformis DW2[J].Research in Microbiology, 2017, 168(6):515-523.
[27] STONE K J, STROMINGER J L.Mechanism of action of bacitracin:Complexation with metal ion and C55-isoprenyl pyrophosphate[J].PNAS, 1971, 68(12):3 223-3 227.
[28] LI Y, WU F, CAI D B, et al.Enhanced production of bacitracin by knocking out of amino acid permease gene yhdG in Bacillus licheniformis DW2[J]. Chinese Journal of Biotechnology, 2018, 34(6):916-927.
[29] THEVENARD B, RASOAVA N, FOURCASSIÉ P, et al.Characterization of Streptococcus thermophilus two-component systems:In silico analysis, functional analysis and expression of response regulator genes in pure or mixed culture with its yogurt partner, Lactobacillus delbrueckii subsp.bulgaricus[J].International Journal of Food Microbiology, 2011, 151(2):171-181.
[30] THEVENARD B, BESSET C, CHOINARD S, et al.Response of S.thermophilus LMD-9 to bacitracin:Involvement of a BceRS/AB-like module and of the rhamnose-glucose polysaccharide synthesis pathway[J].International Journal of Food Microbiology, 2014, 177:89-97.
[31] LEMOINE J, CHIRAT F, WIERUSZESKI J M, et al.Structural characterization of the exocellular polysaccharides produced by Streptococcus thermophilus SFi39 and SFi12[J].Applied and Environmental Microbiology, 1997, 63(9):3 512-3 518.
[32] ZOTTA T, RICCIARDI A, CIOCIA F, et al.Diversity of stress responses in dairy thermophilic streptococci[J].International Journal of Food Microbiology, 2008, 124(1):34-42.
[33] ZOTTA T, ASTERINOU K, ROSSANO R, et al.Effect of inactivation of stress response regulators on the growth and survival of Streptococcus thermophilus Sfi39[J].International Journal of Food Microbiology, 2009, 129(3):211-220.
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