A ultra-performance liquid chromatography tandem mass spectrometry (UPLC-MS/MS) was established for the simultaneous analysis of 41 pesticides and seven mycotoxins in wine. The samples were purified with QuEChERS, and detected by UPLC-MS/MS. Some compounds were quantified by external standard method. All 48 substances showed good linearity in their linear range, the correlation coefficients were greater than 0.999, The limits of detection ranged from 0.01 μg/kg to 5 μg/kg, and the limits of quantification ranged from 0.05 μg/kg to 17 μg/kg. The average recoveries at three spiked levels of 25, 50 and 80 μg/kg were 79.6%-122.5%, with relative standard deviations(RSD) of 0.21%-6.39% (n=6). Thus, the optimized method has simple, high efficiency, good stability, and it can be widely used in the rapid screening and quantitative detection of multiple drug residues in wine.
ZHOU Chunhong
,
PENG Wenjing
. Determination of 41 pesticides and 7 mycotoxins in wine by ultra-performance liquid chromatography tandem mass spectrometry in multiple reaction monitoring mode[J]. Food and Fermentation Industries, 2023
, 49(4)
: 264
-267
.
DOI: 10.13995/j.cnki.11-1802/ts.030609
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