Structures and effects of Hericium erinaceus polysaccharide on regulating gut microbiota: A review

  • ZHU Jiamin ,
  • WU Yi ,
  • ZHAO Linjing ,
  • SHEN Fanni ,
  • CAO Tingwei ,
  • LIU Xiaohui ,
  • LIU Xijian ,
  • LI Hongsen ,
  • LI Qi ,
  • FENG Meiqing
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  • 1(College of Chemistry and Chemical Engineering, Shanghai University of Engineering Science, Shanghai 201620, China)
    2(Shanghai Leiyunshang Pharmaceutical Co. Ltd., Shanghai 201401, China)
    3(School of Pharmacy, Fudan University, Shanghai 201203, China)

Received date: 2023-03-23

  Revised date: 2023-04-11

  Online published: 2023-08-30

Abstract

Hericium erinaceus polysaccharide is a kind of biological macromolecule extracted from the fruiting body, mycelium or fermentation broth of the culinary and medicinal mushroom of H. erinaceus. In recent years, more and more studies have shown the roles of H. erinaceus polysaccharide in immune regulation, alleviating inflammatory bowel disease, and improving nervous system and metabolic diseases by mediating gut microbiota. H. erinaceus polysaccharide possess a variety of health promoting effects by enriching the intestinal probiotics, inhibiting the growth of pathogenic bacteria, improving the production of short-chain fatty acids, enhancing intestinal immune responses, and activating the specific signaling pathways. These biological activities are related to the structure of H. erinaceus polysaccharide. This review summarized the structural characteristics of H. erinaceus polysaccharide from different sources and the influence on gut microbiota diversity, the effects and potential mechanism on promoting health by regulating intestinal flora, as well as the applications and development prospects in various fields. It could provide a theoretical basis for further study of H. erinaceus polysaccharides on gut microbial homeostasis, and give a reference for developing and utilizing H. erinaceus polysaccharides as promising prebiotics.

Cite this article

ZHU Jiamin , WU Yi , ZHAO Linjing , SHEN Fanni , CAO Tingwei , LIU Xiaohui , LIU Xijian , LI Hongsen , LI Qi , FENG Meiqing . Structures and effects of Hericium erinaceus polysaccharide on regulating gut microbiota: A review[J]. Food and Fermentation Industries, 2023 , 49(14) : 311 -320 . DOI: 10.13995/j.cnki.11-1802/ts.035592

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