Research progress and prospects of time-restricted eating for metabolic health

  • LUO Changwei ,
  • LIAO Yuesheng ,
  • XU Zhen
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  • (School of Physical Education, Jiangxi University of Technology, Nanchang 330098, China)

Received date: 2022-09-13

  Revised date: 2022-11-13

  Online published: 2023-09-27

Abstract

With the changes in people’s lifestyles and dietary structures, the prevalence of metabolic diseases such as fatty liver, diabetes, and obesity has increased significantly, seriously endangering the physical and mental health of residents. Research on healthy, universal, and scientific dietary patterns has become a key topic of concern in the current society. Time-restricted eating (TRE) is a dietary pattern that restricts the daily eating time, usually limiting the daily eating time to 4-12 h to extend the time in the fasting state. This pattern is widely praised for its benefits in weight loss, glucose tolerance improvement, and metabolic disorder regulation. Therefore, this paper searched and sorted the relevant literature from the official websites of China National Knowledge Infrastructure (CNKI), PubMed, Web of Science, the World Health Organization, and other relevant databases, analyzed the clinical evidence and potential mechanism of TRE in promoting metabolic health, and put forward prospects, to provide a certain reference for the application of TRE in the prevention and treatment of metabolic diseases.

Cite this article

LUO Changwei , LIAO Yuesheng , XU Zhen . Research progress and prospects of time-restricted eating for metabolic health[J]. Food and Fermentation Industries, 2023 , 49(17) : 348 -353 . DOI: 10.13995/j.cnki.11-1802/ts.033620

References

[1] HOFFMAN D J, POWELL T L, BARRETT E S, et al.Developmental origins of metabolic diseases[J].Physiological Reviews, 2021, 101(3):739-795.
[2] MCCUEN-WURST C, RUGGIERI M, ALLISON K C.Disordered eating and obesity:Associations between binge-eating disorder, night-eating syndrome, and weight-related comorbidities[J].Annals of the New York Academy of Sciences, 2018, 1411(1):96-105.
[3] DUREGON E, POMATTO-WATSON L C D D, BERNIER M, et al.Intermittent fasting:From calories to time restriction[J].GeroScience, 2021, 43(3):1083-1092.
[4] CRUPI A N, HAASE J, BRANDHORST S, et al.Periodic and intermittent fasting in diabetes and cardiovascular disease[J].Current Diabetes Reports, 2020, 20(12):83.
[5] LOWE D A, WU N, ROHDIN-BIBBY L, et al.Effects of time-restricted eating on weight loss and other metabolic parameters in women and men with overweight and obesity:The TREAT randomized clinical trial[J].JAMA Internal Medicine, 2020, 180(11):1491-1499.
[6] WILKINSON M J, MANOOGIAN E N C, ZADOURIAN A, et al.Ten-hour time-restricted eating reduces weight, blood pressure, and atherogenic lipids in patients with metabolic syndrome[J].Cell Metabolism, 2020, 31(1):92-104.e5.
[7] MANOOGIAN E N C, PANDA S.Circadian rhythms, time-restricted feeding, and healthy aging[J].Ageing Research Reviews, 2017, 39:59-67.
[8] STOCKMAN M C, THOMAS D, BURKE J, et al.Intermittent fasting:Is the wait worth the weight?[J].Current Obesity Reports, 2018, 7(2):172-185.
[9] DE CABO R, MATTSON M P.Effects of intermittent fasting on health, aging, and disease[J].The New England Journal of Medicine, 2019, 381(26):2541-2551.
[10] ADAFER R, MESSAADI W, MEDDAHI M, et al.Food timing, circadian rhythm and chrononutrition:A systematic review of time-restricted eating’s effects on human health[J].Nutrients, 2020, 12(12):3770.
[11] LIU D Y, HUANG Y, HUANG C, et al.Calorie Restriction with or without Time-Restricted Eating in Weight Loss[J].The New England Journal of Medicine, 2022, 386(16):1495-1504.
[12] GABEL K, HODDY K K, HAGGERTY N, et al.Effects of 8-hour time restricted feeding on body weight and metabolic disease risk factors in obese adults:A pilot study[J].Nutrition and Healthy Aging, 2018, 4(4):345-353.
[13] PHILLIPS N, MARESCHAL J, SCHWAB N, et al.The effects of time-restricted eating versus standard dietary advice on weight, metabolic health and the consumption of processed food:A pragmatic randomised controlled trial in community-based adults[J].Nutrients, 2021, 13(3):1042.
[14] HONMA S.Development of the mammalian circadian clock[J]. European Journal of Neuroscience, 2020, 51(1):182-193.
[15] DE ASSIS L V M, OSTER H.The circadian clock and metabolic homeostasis:Entangled networks[J].Cellular and Molecular Life Sciences, 2021, 78(10):4563-4587.
[16] TARQUINI R, MAZZOCCOLI G.Clock genes, metabolism, and cardiovascular risk[J].Heart Failure Clinics, 2017, 13(4):645-655.
[17] VIEIRA E, MIRIZIO G G, BARIN G R, et al.Clock genes, inflammation and the immune system-implications for diabetes, obesity and neurodegenerative diseases[J].International Journal of Molecular Sciences, 2020, 21(24):9743.
[18] DAMIOLA F, MINH N L, PREITNER N, et al.Restricted feeding uncouples circadian oscillators in peripheral tissues from the central pacemaker in the suprachiasmatic nucleus[J].Genes & Development, 2000, 14(23):2950-2961.
[19] KARATSOREOS I N, BHAGAT S, BLOSS E B, et al.Disruption of circadian clocks has ramifications for metabolism, brain, and behavior[J].Proceedings of the National Academy of Sciences of the United States of America, 2011, 108(4):1657-1662.
[20] HA K, SONG Y.Associations of meal timing and frequency with obesity and metabolic syndrome among Korean adults[J].Nutrients, 2019, 11(10):2437.
[21] YOSHIDA J, EGUCHI E, NAGAOKA K, et al.Association of night eating habits with metabolic syndrome and its components:A longitudinal study[J].BMC Public Health, 2018, 18(1):1366.
[22] CHAIX A, ZARRINPAR A, MIU P, et al.Time-restricted feeding is a preventative and therapeutic intervention against diverse nutritional challenges[J].Cell Metabolism, 2014, 20(6):991-1005.
[23] HATORI M, VOLLMERS C, ZARRINPAR A, et al.Time-restricted feeding without reducing caloric intake prevents metabolic diseases in mice fed a high-fat diet[J].Cell Metabolism, 2012, 15(6):848-860.
[24] YASUMOTO Y, HASHIMOTO C, NAKAO R, et al.Short-term feeding at the wrong time is sufficient to desynchronize peripheral clocks and induce obesity with hyperphagia, physical inactivity and metabolic disorders in mice[J].Metabolism, 2016, 65(5):714-727.
[25] SUTTON E F, BEYL R, EARLY K S, et al.Early time-restricted feeding improves insulin sensitivity, blood pressure, and oxidative stress even without weight loss in men with prediabetes[J].Cell Metabolism, 2018, 27(6):1212-1221.
[26] PARR E B, DEVLIN B L, RADFORD B E, et al.A delayed morning and earlier evening time-restricted feeding protocol for improving glycemic control and dietary adherence in men with overweight/obesity:A randomized controlled trial[J].Nutrients, 2020, 12(2):505.
[27] HUTCHISON A T, REGMI P, MANOOGIAN E N C, et al.Time-restricted feeding improves glucose tolerance in men at risk for type 2 diabetes:A randomized crossover trial[J].Obesity, 2019:oby.22449
[28] JAMSHED H, BEYL R A, DELLA MANNA D L, et al.Early time-restricted feeding improves 24-hour glucose levels and affects markers of the circadian clock, aging, and autophagy in humans[J].Nutrients, 2019, 11(6):1234.
[29] TINSLEY G M, FORSSE J S, BUTLER N K, et al.Time-restricted feeding in young men performing resistance training:A randomized controlled trial[J].European Journal of Sport Science, 2017, 17(2):200-207.
[30] GABEL K, MARCELL J, CARES K, et al.Effect of time restricted feeding on the gut microbiome in adults with obesity:A pilot study[J].Nutrition and Health, 2020, 26(2):79-85.
[31] ZEB F, WU X Y, CHEN L J, et al.Effect of time-restricted feeding on metabolic risk and circadian rhythm associated with gut microbiome in healthy males[J].British Journal of Nutrition, 2020, 123(11):1216-1226.
[32] ISENMANN E, DISSEMOND J, GEISLER S.The effects of a macronutrient-based diet and time-restricted feeding (16∶8) on body composition in physically active individuals-a 14-week randomised controlled trial[J].Nutrients, 2021, 13(9):3122.
[33] CARLSON O, MARTIN B, STOTE K S, et al.Impact of reduced meal frequency without caloric restriction on glucose regulation in healthy, normal-weight middle-aged men and women[J].Metabolism, 2007, 56(12):1729-1734.
[34] MORO T, TINSLEY G, BIANCO A, et al.Effects of eight weeks of time-restricted feeding (16/8) on basal metabolism, maximal strength, body composition, inflammation, and cardiovascular risk factors in resistance-trained males[J].Journal of Translational Medicine, 2016, 14(1):290.
[35] JONES R, PABLA P, MALLINSON J, et al.Two weeks of early time-restricted feeding (eTRF) improves skeletal muscle insulin and anabolic sensitivity in healthy men[J].The American Journal of Clinical Nutrition, 2020, 112(4):1015-1028.
[36] LI C Z, XING C, ZHANG J Q, et al.Eight-hour time-restricted feeding improves endocrine and metabolic profiles in women with anovulatory polycystic ovary syndrome[J].Journal of Translational Medicine, 2021, 19(1):148-156.
[37] CIENFUEGOS S, GABEL K, KALAM F, et al.Effects of 4- and 6-h time-restricted feeding on weight and cardiometabolic health:A randomized controlled trial in adults with obesity[J].Cell Metabolism, 2020, 32(3):366-378.
[38] PATTERSON R E, LAUGHLIN G A, LACROIX A Z, et al.Intermittent fasting and human metabolic health[J].Journal of the Academy of Nutrition and Dietetics, 2015, 115(8):1203-1212.
[39] PETERSEN M C, SHULMAN G I.Mechanisms of insulin action and insulin resistance[J].Physiological Reviews, 2018, 98(4):2133-2223.
[40] MARCHEVA B, RAMSEY K M, BUHR E D, et al.Disruption of the clock components CLOCK and BMAL1 leads to hypoinsulinaemia and diabetes[J].Nature, 2010, 466(7306):627-631.
[41] PERELIS M, MARCHEVA B, RAMSEY K M, et al.Pancreatic β cell enhancers regulate rhythmic transcription of genes controlling insulin secretion[J].Science, 2015, 350(6261):aac4250.
[42] RUBIN N H, ALINDER G, RIETVELD W J, et al.Restricted feeding schedules alter the circadian rhythms of serum insulin and gastric inhibitory polypeptide[J].Regulatory Peptides, 1988, 23(3):279-288.
[43] CATRYSSE L, VAN LOO G.Inflammation and the metabolic syndrome:The tissue-specific functions of NF-κB[J].Trends in Cell Biology, 2017, 27(6):417-429.
[44] REN J J, HU D D, MAO Y L, et al.Alteration in gut microbiota caused by time-restricted feeding alleviate hepatic ischaemia reperfusion injury in mice[J].Journal of Cellular and Molecular Medicine, 2019, 23(3):1714-1722.
[45] CHAIX A, MANOOGIAN E N C, MELKANI G C, et al.Time-restricted eating to prevent and manage chronic metabolic diseases[J].Annual Review of Nutrition, 2019, 39:291-315.
[46] INOKI K, KIM J, GUAN K L.AMPK and mTOR in cellular energy homeostasis and drug targets[J].Annual Review of Pharmacology and Toxicology, 2012, 52:381-400.
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