Omega fatty acid is of particular interest in terms of theirs effects on intestinal microflora with different concentration and saturation. Although the effect of omega-3 on the human gut microbiota has been discussed in several studies, the results and discussion of the inability to standardize in human’s gut and the absence of integrated unsaturation are still insufficient. In this study, lab-made the new dynamic model bionic gastrointestinal reactor be applied to instantiate stand objects. DHA, AA and coconut oil were selected from omega-3 and 6 groups of fatty acids, and used as research objects. The effects of different concentrations and saturation of fatty acids on the intestinal flora and metabolism were studied by anaerobic fermentation in vitro. The results showed that the concentrations of short-chain fatty acid such as acetic acid, propionic acid and butyric acid in DHA group were 54.79, 8.34, and 1.45 mmol/L, respectively. Compared with the positive control group, the changes were 11.48%, -1.41% and 66.98%, respectively, and the moderate DHA group also stabilized the intestinal flora and up-regulated the beneficial bacteria such as Acinetobacter and Bifidobacterium. It showed that low saturation had more significant effect on reducing the abundance of pathogenic bacteria and increasing the abundance of probiotics than high saturation. The results suggest that low-saturated fatty acid DHA has a positive effect on the intestinal flora of healthy adults.
ZHU Ling
,
YIN Zhongwei
,
LI Huan
,
LI Zhitao
,
ZHU Li
,
ZHAN Xiaobei
. In vitro fermentation characteristics of unsaturated fatty acids and its effect on intestinal flora based on bionic gastrointestinal digestion technology[J]. Food and Fermentation Industries, 2023
, 49(21)
: 45
-51
.
DOI: 10.13995/j.cnki.11-1802/ts.034659
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