Food and Fermentation Industries >

2023 , Vol. 49 >Issue 22: 199 - 207

DOI: https://doi.org/10.13995/j.cnki.11-1802/ts.034468

Analysis on formula regularity and quality control of health food containing Lycium barbarum extract based on data mining and complex network

  • WANG Yu ,
  • REN Xueyang ,
  • LI Liuyang ,
  • SUN Jintao ,
  • BAO Kaixin ,
  • ZHONG Xiangjian ,
  • SONG Ruolan ,
  • ZHENG Yuan ,
  • SHAN Dongjie ,
  • LYU Fang ,
  • DENG Qingyue ,
  • LI Xianxian ,
  • HE Yingyu ,
  • SHE Gaimei
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  • (Beijing University of Chinese Medicine, Beijing 100029, China)

Received date: 2022-11-28

  Revised date: 2023-01-12

  Online published: 2023-12-25

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Abstract

This study aimed to explore the formula rule of health food containing Lycium barbarum extract (LBE) and to analyze its quality control status. Through searching the information on health food containing LBE on the State Administration for Market Regulation and Pharmaceutical Intelligence data network, and using complex network and association rule analysis, the formula regularity of health food containing LBE was summarized. At the same time, its quality control status was analyzed based on the literature. Results showed that 208 health foods containing LBE included 17 health functions and 138 raw materials, and they were divided into 8 communities. Combined with traditional Chinese medicine theory, 8 therapeutical principles were summarized. Enhancing immunity and alleviating physical fatigue were the main health functions. The most commonly used combinations of the former were Ganoderma extract-Panacis Quinquefolii Radix, Astragali Radix extract-Panacis Quinquefolii Radix, and Astragali Radix extract-Polygonati Rhizoma extract. The common combinations of the latter were Panacis Quinquefolii Radix extract-Acanthopanacis Senticosi Radix et Rhizoma Seu Caulis extract, Cervi Cornu Pantotrichum-Ophiopogonis Radix extract, and Panacis Quinquefolii Radix extract-Ophiopogonis Radix extract. 208 health foods containing LBE included 55 functional components, and the frequency of crude polysaccharides was the highest (137 times). At present, there is no unified standard for the quality control of LBE. There are a few related studies, mainly including the determination of polysaccharide content and the analysis of monosaccharide composition. Data mining and complex network analysis can provide new ideas for researching and developing healthy food. The quality control of LBE and its health food needs to be further studied, and the combination of various analytical techniques may be a new direction for their quality control.

Key words： Lycium barbarum extract; health food; formula rule; quality control; data mining; complex network analysis

Cite this article

WANG Yu , REN Xueyang , LI Liuyang , SUN Jintao , BAO Kaixin , ZHONG Xiangjian , SONG Ruolan , ZHENG Yuan , SHAN Dongjie , LYU Fang , DENG Qingyue , LI Xianxian , HE Yingyu , SHE Gaimei . Analysis on formula regularity and quality control of health food containing Lycium barbarum extract based on data mining and complex network[J]. Food and Fermentation Industries, 2023 , 49(22) : 199 -207 . DOI: 10.13995/j.cnki.11-1802/ts.034468

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