Food and Fermentation Industries >

2023 , Vol. 49 >Issue 22: 311 - 317

DOI: https://doi.org/10.13995/j.cnki.11-1802/ts.034911

Application of metabolomics in the study of foodborne pathogenic Vibrio spp.

  • ZHAO Yanni ,
  • WU Ruobing ,
  • YU Rui ,
  • ZHANG Senhu ,
  • LI Hua ,
  • LIU Huan
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  • 1(College of Food and Biological Engineering, Shaanxi University of Science & Technology, Xi’an 710021, China)
    2(SUSTech Core Research Facilities, Southern University of Technology, Shenzhen 518055,China)

Received date: 2023-01-16

  Revised date: 2023-02-16

  Online published: 2023-12-25

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Abstract

Vibrio spp. is a main foodborne pathogen in marine aquaculture industry, which can cause serious threat to the sustainable development of aquatic products and human health. Currently, antibiotics is important for preventing and controlling Vibrio spp. in aquaculture, yet there are safety concerns regarding antimicrobial resistance. The development of new antibiotic alternatives (e.g. plant-derived bacteriostatic agents, biological peptides, vaccines, etc.) is inseparable from basic research works such as the pathogenic mechanism and virulence regulation mechanism of Vibrio spp. Metabolomics is the determination of dynamic multivariate metabolic response of biological systems to external environmental stimuli or internal genetic changes. At present, metabolomics technology is widely applied to study the interaction between Vibrio spp. and host, clarify the relationship between the physiological functions of Vibrio spp. and metabolites, and screen biomarkers of Vibrio spp. inducing host diseases, so as to reveal the pathogenic mechanism of Vibrio spp. and explore new potential antibacterial therapeutic targets. Herein, we introduce the analysis method, analysis process and applications of metabolomics technology for foodborne pathogenic Vibrio spp., in order to provide a new perspective for the pathogenic mechanism investigation of foodborne Vibrio spp. and supply references for the development of new technologies for prevention and control of mariculture diseases.

Key words： Vibrio spp.; metabolomics; pathogenesis; therapeutic target

Cite this article

ZHAO Yanni , WU Ruobing , YU Rui , ZHANG Senhu , LI Hua , LIU Huan . Application of metabolomics in the study of foodborne pathogenic Vibrio spp.[J]. Food and Fermentation Industries, 2023 , 49(22) : 311 -317 . DOI: 10.13995/j.cnki.11-1802/ts.034911

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