Research progress on the regulation mechanism of biofilm of foodborne Vibrio parahaemolyticus

  • TANG Jialing ,
  • GUO Xinglan ,
  • RAO Junyue ,
  • YANG Maojie ,
  • CAO Yunrong ,
  • HAN Guoquan
Expand
  • 1(College of Food Science, Sichuan Agricultural University, Ya′an 625014, China)
    2(Sichuan Agricultural University Institute of Food Processing and Safety, Ya′an 625014, China)

Received date: 2023-03-06

  Revised date: 2023-03-17

  Online published: 2024-01-17

Abstract

Vibrio parahaemolyticus is a foodborne pathogenic bacteria that widely exists in marine products and can cause acute gastroenteritis in humans, which greatly endangers human health. Biofilm is a kind of highly resistant form produced by bacteria in the face of extreme environment, and has natural resistance to antibiotics and body immunity. Common disinfection methods cannot completely eliminate it. When V. parahaemolyticus forms biofilm, it will cause more serious harm to human health and food industry. This review mainly elaborates the relevant signal molecules that affect the formation of biofilm of V. parahaemolyticus from the three regulatory factors of cyclic guanosine acid, quorum sensing system, and two-component system, and focuses on the regulatory mechanism of signal molecules in the formation process, which is necessary to further reveal the mechanism of several regulatory factors regulating biofilm formation. It is expected to provide theoretical basis for food safety, microbial prevention and control, and help to find the control method of V. parahaemolyticus biofilm.

Cite this article

TANG Jialing , GUO Xinglan , RAO Junyue , YANG Maojie , CAO Yunrong , HAN Guoquan . Research progress on the regulation mechanism of biofilm of foodborne Vibrio parahaemolyticus[J]. Food and Fermentation Industries, 2023 , 49(24) : 372 -380 . DOI: 10.13995/j.cnki.11-1802/ts.035344

References

[1] 刘伟, 尹可欣, 施丽飞, 等. 北京市海淀区2010—2019年食源性疾病暴发检测结果分析[J]. 海峡预防医学杂志, 2022, 28(1):91-93.
LIU W, YIN K X, SHI L F, et al. Analysis on detection results of foodborne disease outbreaks in Haidian District of Beijing City, 2010-2019[J]. Strait Journal of Preventive Medicine, 2022, 28(1):91-93.
[2] 姚利利, 何平, 沈先标, 等. 2015—2018年上海市宝山区食源性疾病病原监测结果分析[J]. 职业与健康, 2020, 36(1):38-41.
YAO L L, HE P, SHEN X B, et al. Analysis on monitoring results of foodborne disease pathogens in Baoshan District of Shanghai from 2015-2018[J]. Occupation and Health, 2020, 36(1):38-41.
[3] 强鑫华, 周丽华, 王萍, 等. 2016年-2017年湖州地区食源性疾病病原菌检出分析[J]. 中国卫生检验杂志, 2020, 30(9):1118-1120.
QIANG X H, ZHOU L H, WANG P, et al. Detection and analysis of pathogenic bacteria in food-borne diseases from 2016 to 2017 in Huzhou[J]. Chinese Journal of Health Laboratory Technology, 2020, 30(9):1118-1120.
[4] 李文毅. 2016—2018年无锡市梁溪区食源性疾病监测报告[J]. 江苏预防医学, 2022, 33(2):197-199.
LI W Y. Surveillance report on food-borne diseases in Liangxi district of Wuxi city from 2016 to 2018[J]. Jiangsu Journal of Preventive Medicine, 2022, 33(2):197-199.
[5] 许金凤, 张潇丹, 巢秀琴, 等. 2017—2019年镇江地区哨点医院食源性疾病病原监测结果[J]. 江苏预防医学, 2022, 33(4):469-471.
XU J F, ZHANG X D, CHAO X Q, et al. Surveillance results of food-borne diseases in sentinel hospitals in Zhenjiang from 2017 to 2019[J]. Jiangsu Journal of Preventive Medicine, 2022, 33(4):469-471.
[6] 孙雅娜, 刘坚龄, 梁广忠, 等. 2018—2020年天津市津南区食源性致病菌分布及药敏分析[J]. 中国食品卫生杂志, 2021, 33(5):548-552.
SUN Y N, LIU J L, LIANG G Z, et al. Distribution and drug sensitivity analysis of foodborne pathogens in Jinnan District of Tianjin from 2018 to 2020[J]. Chinese Journal of Food Hygiene, 2021, 33(5):548-552.
[7] 王雪娇, 刘钦, 赵苗苗, 等. 2016—2020年天津市滨海新区食源性疾病监测结果分析[J]. 职业与健康, 2022, 38(12):1637-1641.
WANG X J, LIU Q, ZHAO M M, et al. Analysis on surveillance results of foodborne diseases in Tianjin Binhai New Area from 2016-2020[J]. Occupation and Health, 2022, 38(12):1637-1641.
[8] 刘爱萍. 细菌生物膜与食品安全[J]. 肉类工业, 2007(8):34-35.
LIU A P. Bacterial biofilm and food safety[J]. Meat Industry, 2007(8):34-35.
[9] ASHRAFUDOULLA M, MIZAN M F R, PARK H, et al. Genetic relationship, virulence factors, drug resistance profile and biofilm formation ability of Vibrio parahaemolyticus isolated from mussel[J]. Frontiers in Microbiology, 2019, 10:513.
[10] 陈萍. 副溶血性弧菌-单增李斯特菌共培养下混合生物被膜形成及种间关系的研究[D]. 上海: 上海海洋大学, 2020.
CHEN P. Mixed biofilm formation and the interspecies relationship between V.parahaemolyticus and L.monocytogenes[D]. Shanghai: Shanghai Ocean University, 2020.
[11] MAHAMUNI-BADIGER P P, PATIL P M, BADIGER M V, et al. Biofilm formation to inhibition: Role of zinc oxide-based nanoparticles[J]. Materials Science and Engineering: C, 2020, 108:110319.
[12] 李安琪. 副溶血性弧菌生物膜形成机制及其防控策略研究[D]. 芜湖: 安徽工程大学, 2022.
LI A Q. Study on the mechanism of Vibrio parahaemolyticus biofilm formation and its prevention and control strategies[D]. Wuhu: Anhui Polytechnic University, 2022.
[13] KARAOLIS D K R, CHENG K R, LIPSKY M, et al. 3′, 5′-Cyclic diguanylic acid (c-di-GMP) inhibits basal and growth factor-stimulated human colon cancer cell proliferation[J]. Biochemical and Biophysical Research Communications, 2005, 329(1):40-45.
[14] YU M, CHUA S L. Demolishing the great wall of biofilms in Gram-negative bacteria: To disrupt or disperse?[J]. Medicinal Research Reviews, 2020, 40(3):1103-1116.
[15] DAHLSTROM K M, O′TOOLE G A. A symphony of cyclases: Specificity in diguanylate cyclase signaling[J]. Annual Review of Microbiology, 2017, 71:179-195.
[16] STEINER S, LORI C, BOEHM A, et al. Allosteric activation of exopolysaccharide synthesis through cyclic di-GMP-stimulated protein-protein interaction[J]. The EMBO Journal, 2013, 32(3):354-368.
[17] LEE E R, BAKER J L, WEINBERG Z, et al. An allosteric self-splicing ribozyme triggered by a bacterial second messenger[J]. Science, 2010, 329(5993):845-848.
[18] JENAL U, REINDERS A, LORI C. Cyclic di-GMP: Second messenger extraordinaire[J]. Nature Reviews. Microbiology, 2017, 15(5):271-284.
[19] SUNDRIYAL A, MASSA C, SAMORAY D, et al. Inherent regulation of EAL domain-catalyzed hydrolysis of second messenger cyclic di-GMP[J]. The Journal of Biological Chemistry, 2014, 289(10):6978-6990.
[20] NAVARRO M V A S, NEWELL P D, KRASTEVA P V, et al. Structural basis for c-di-GMP-mediated inside-out signaling controlling periplasmic proteolysis[J]. PLoS Biology, 2011, 9(2): e1000588.
[21] POVOLOTSKY T L, HENGGE R. ‘Life-style’ control networks in Escherichia coli: Signaling by the second messenger c-di-GMP[J]. Journal of Biotechnology, 2012, 160(1-2):10-16.
[22] FAGERLUND A, SMITH V, RØHR Å K, et al. Cyclic diguanylate regulation of Bacillus cereus group biofilm formation[J]. Molecular Microbiology, 2016, 101(3):471-494.
[23] GALPERIN M Y. Diversity of structure and function of response regulator output domains[J]. Current Opinion in Microbiology, 2010, 13(2):150-159.
[24] KALIA D, MEREY G, NAKAYAMA S, et al. Nucleotide, c-di-GMP, c-di-AMP, cGMP, cAMP, (p)ppGpp signaling in bacteria and implications in pathogenesis[J]. Chemical Society Reviews, 2013, 42(1):305-341.
[25] GALPERIN M Y, NIKOLSKAYA A N, KOONIN E V. Novel domains of the prokaryotic two-component signal transduction systems[J]. FEMS Microbiology Letters, 2001, 203(1):11-21.
[26] TRIMBLE M J, MCCARTER L L. Bis-(3′-5′)-cyclic dimeric GMP-linked quorum sensing controls swarming in Vibrio parahaemolyticus[J]. Proceedings of the National Academy of Sciences of the United States of America, 2011, 108(44):18079-18084.
[27] FERREIRA R B R, ANTUNES L C M, GREENBERG E P, et al. Vibrio parahaemolyticus ScrC modulates cyclic dimeric GMP regulation of gene expression relevant to growth on surfaces[J]. Journal of Bacteriology, 2008, 190(3):851-860.
[28] 欧杰, 王秋钰, 黄奥迪, 等. 水产品中弧菌生物被膜的形成及调控机制[J]. 水产学报, 2022: 1-11.
OU J, WANG Q Y, HUANG A D, et al. Formation and regulation mechanism of Vibrio biofilm in aquatic products[J]. Journal of Fisheries, 2022: 1-11.
[29] GODE-POTRATZ C J, KUSTUSCH R J, BREHENY P J, et al. Surface sensing in Vibrio parahaemolyticus triggers a programme of gene expression that promotes colonization and virulence[J]. Molecular Microbiology, 2011, 79(1):240-263.
[30] FERNICOLA S, TORQUATI I, PAIARDINI A, et al. Synthesis of triazole-linked analogues of c-di-GMP and their interactions with diguanylate cyclase[J]. Journal of Medicinal Chemistry, 2015, 58(20):8269-8284.
[31] ZHENG Y E, TSUJI G, OPOKU-TEMENG C, et al. Inhibition of P.aeruginosa c-di-GMP phosphodiesterase RocR and swarming motility by a benzoisothiazolinone derivative[J]. Chemical Science, 2016, 7(9):6238-6244.
[32] TUCKERMAN J R, GONZALEZ G, SOUSA E H S, et al. An oxygen-sensing diguanylate cyclase and phosphodiesterase couple for c-di-GMP control[J]. Biochemistry, 2009, 48(41):9764-9774.
[33] RYU M H, FOMICHEVA A, O’NEAL L, et al. Using Light-Activated Enzymes for Modulating Intracellular C-Di-GMP Levels in Bacteria[M]//c-di-GMP Signaling. New York, NY: Springer New York, 2017:169-186.
[34] LAGANENKA L, SOURJIK V. Autoinducer 2-dependent Escherichia coli biofilm formation is enhanced in a dual-species coculture[J]. Applied and Environmental Microbiology, 2018, 84(5): e02638-e02617.
[35] 莫祯妮, 熊盈盈, 邱树毅, 等. 群体感应抑制剂调控食源性微生物生物膜形成的研究进展[J]. 食品科学, 2021, 42(17):307-316.
MO Z N, XIONG Y Y, QIU S Y, et al. Progress in quorum sensing inhibitors in regulating biofilm formation of foodborne microorganisms[J]. Food Science, 2021, 42(17):307-316.
[36] ZHU Y L, LI C Z, CUI H Y, et al. Feasibility of cold plasma for the control of biofilms in food industry[J]. Trends in Food Science & Technology, 2020, 99:142-151.
[37] 孔凡栋,周丽曼,马青云,等.革兰阳性细菌AIP型群体感应抑制剂的研究进展[J].热带生物学报,2017,8(2):236-240.
KONG F D, ZHOU L M, MA Q Y, et al. Research advances in the AIP-based quorum sensing inhibitors of gram-positive bacteria[J]. Journal of Tropical Biology, 2017, 8(2):236-240.
[38] SCHAUDER S, SHOKAT K, SURETTE M G, et al. The LuxS family of bacterial autoinducers: Biosynthesis of a novel quorum-sensing signal molecule[J]. Molecular Microbiology, 2001, 41(2):463-476.
[39] 高敏. 细菌群体感应信号分子(AHLs)的释放模式及其对生物膜形成的强化作用[D]. 西安: 西安建筑科技大学, 2019.
GAO M. Study on the release pattern of quorum sensing signaling molecules (AHLs) for bacteria and their bioaugmentation during biofilm formation process[D]. Xi′an: Xi′an University of Architecture and Technology, 2019.
[40] 薛挺. 大肠杆菌及金黄色葡萄球菌AI-2群体感应系统的调控研究[D]. 合肥: 中国科学技术大学, 2009.
XUE T. Regulatory mode of AI-2 quorum sensing system in Escherichia coli and Staphylococcus aureus[D]. Hefei: University of Science and Technology of China, 2009.
[41] BANERJEE G, RAY A K. The talking language in some major Gram-negative bacteria[J]. Archives of Microbiology, 2016, 198(6):489-499.
[42] 廉雪花. 酸马奶酒中乳酸菌产AI-2信号分子的研究[D]. 呼和浩特: 内蒙古农业大学, 2014.
LIAN X H. Study of AI-2Signal molecule in lactic acid bacteria from koumiss[D]. Hohhot: Inner Mongolia Agricultural University, 2014.
[43] STURME M H J, KLEEREBEZEM M, NAKAYAMA J, et al. Cell to cell communication by autoinducing peptides in gram-positive bacteria[J]. Antonie Van Leeuwenhoek, 2002, 81(1):233-243.
[44] ASAD S, OPAL S M. Bench-to-bedside review: Quorum sensing and the role of cell-to-cell communication during invasive bacterial infection[J]. Critical Care, 2008, 12(6):1-11.
[45] ZHANG Y Q, QIU Y, GAO H, et al. OpaR controls the metabolism of c-di-GMP in Vibrio parahaemolyticus[J]. Frontiers in Microbiology, 2021, 12:676436.
[46] BALL A S, CHAPARIAN R R, VAN KESSEL J C. Quorum sensing gene regulation by LuxR/HapR master regulators in vibrios[J]. Journal of Bacteriology, 2017, 199(19): e00105-e00117.
[47] WANG L, LING Y, JIANG H W, et al. AphA is required for biofilm formation, motility, and virulence in pandemic Vibrio parahaemolyticus[J]. International Journal of Food Microbiology, 2013, 160(3):245-251.
[48] ZHOU D S, YAN X J, QU F, et al. Quorum sensing modulates transcription of cpsQ-mfpABC and mfpABC in Vibrio parahaemolyticus[J]. International Journal of Food Microbiology, 2013, 166(3):458-463.
[49] OUYANG J, SUN F, FENG W, et al. Quercetin is an effective inhibitor of quorum sensing, biofilm formation and virulence factors in Pseudomonas aeruginosa[J]. Journal of Applied Microbiology, 2016, 120(4):966-974.
[50] HAN X P, CHEN Q Y, ZHANG X G, et al. Antibiofilm and antiquorum sensing potential of Lactiplantibacillus plantarum Z057 against Vibrio parahaemolyticus[J]. Foods, 2022, 11(15):2230.
[51] PANDE G S J, SCHEIE A A, BENNECHE T, et al. Quorum sensing-disrupting compounds protect larvae of the giant freshwater prawn Macrobrachium rosenbergii from Vibrio harveyi infection[J]. Aquaculture, 2013, 406-407:121-124.
[52] JACOB-DUBUISSON F, MECHALY A, BETTON J M, et al. Structural insights into the signalling mechanisms of two-component systems[J]. Nature Reviews Microbiology, 2018, 16(10):585-593.
[53] STOCK A M, ROBINSON V L, GOUDREAU P N. Two-component signal transduction[J]. Annual Review of Biochemistry, 2000, 69:183-215.
[54] ALI-AHMAD A, FADEL F, SEBBAN-KREUZER C, et al. Structural and functional insights into the periplasmic detector domain of the GacS histidine kinase controlling biofilm formation in Pseudomonas aeruginosa[J]. Scientific Reports, 2017, 7:11262.
[55] HEERMANN R, JUNG K. The complexity of the ‘simple’ two-component system KdpD/KdpE in Escherichia coli[J]. FEMS Microbiology Letters, 2010, 304(2):97-106.
[56] GILMOUR R, FOSTER J E, SHENG Q, et al. New class of competitive inhibitor of bacterial histidine kinases[J]. Journal of Bacteriology, 2005, 187(23):8196-8200.
[57] GONZ#xC1;LEZ A, CASADO J, CHUECA E, et al. Small molecule inhibitors of the response regulator ArsR exhibit bactericidal activity against Helicobacter pylori[J]. Microorganisms, 2020, 8(4):503.
[58] WANG Q Y, WANG P F, LIU P P, et al. Comparative transcriptome analysis reveals regulatory factors involved in Vibrio parahaemolyticus biofilm formation[J]. Frontiers in Cellular and Infection Microbiology, 2022, 12:917131.
[59] WANG L C, MORGAN L K, GODAKUMBURA P, et al. The inner membrane histidine kinase EnvZ senses osmolality via helix-coil transitions in the cytoplasm[J]. The EMBO Journal, 2012, 31(11):2648-2659.
[60] 张艺蓓. EnvZ/OmpR感应Fe3+调控副溶血性弧菌毒力因子的分子机制研究[D]. 杨凌: 西北农林科技大学, 2020.
ZHANG Y B. Study on molecular mechanism of EnvZ/OmpR sensing ferric iron and regulating Vibrio parahaemolyticus virulence factor[D]. Yangling: Northwest A & F University, 2020.
Outlines

/