Food and Fermentation Industries >

2024 , Vol. 50 >Issue 8: 290 - 298

DOI: https://doi.org/10.13995/j.cnki.11-1802/ts.036825

Application of ultra-high-performance liquid chromatography high-resolution mass spectrometry-quantitative analysis of multi-components by single-marker method combined with quality control chart in quality control analysis of high temperature Daqu production process

  • YANG Junlin ,
  • TIAN Dongwei ,
  • WANG Jia ,
  • ZHAO Wenyu ,
  • HUANG Heou ,
  • FAN Endi ,
  • ZHU Anran ,
  • YOU Xiaolong ,
  • WU Cheng ,
  • HU Jianfeng ,
  • WANG Diqiang
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  • (Guizhou Xijiu Co.Ltd., Zunyi 564622, China)

Received date: 2023-07-19

  Revised date: 2023-08-15

  Online published: 2024-06-11

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Abstract

To better monitor the quality of high temperature Daqu in different production stages, the amino acid content of the precursor of important flavor components involved in the fermentation process was comprehensively and accurately controlled.By collecting samples from different batches of high-temperature Daqu in the making workshop, the contents of nine amino acid of important flavor components precursors were determined by ultra-high-performance liquid chromatography high-resolution mass spectrometry-quantitative analysis of multi-components by single-marker method.Meanwhile, quality control charts for high-temperature Daqu quality monitoring under different production stages were established based on Minitab software and the principle of single-value-moving range control chart in the Schwehart control chart.Results showed that the UPLC-HRMS-QAMS method had a good linear relationship (R2>0.997 0) and low detection limit and quantification limit of amino acids to be measured, which could meet the purpose of rapid and accurate qualitative and quantitative analysis of amino acid contents of various important flavor components in high-temperature Daqu.Combined with the quality control chart, the single-value-moving range control chart could be established to monitor the quality changes in the production process of high temperature Daqu, which could provide a new idea for the quality monitoring of high temperature Daqu under different production batches, helped to improve the quality control level of high temperature Daqu, and then provided technical reference for the production process of the workshop, and provided data support and technical guarantee for the realization of high-quality production of enterprises.

Key words： high temperature Daqu; quality control chart; production process; quality control analysis; amino acid

Cite this article

YANG Junlin , TIAN Dongwei , WANG Jia , ZHAO Wenyu , HUANG Heou , FAN Endi , ZHU Anran , YOU Xiaolong , WU Cheng , HU Jianfeng , WANG Diqiang . Application of ultra-high-performance liquid chromatography high-resolution mass spectrometry-quantitative analysis of multi-components by single-marker method combined with quality control chart in quality control analysis of high temperature Daqu production process[J]. Food and Fermentation Industries, 2024 , 50(8) : 290 -298 . DOI: 10.13995/j.cnki.11-1802/ts.036825

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