Food and Fermentation Industries >

2024 , Vol. 50 >Issue 11: 360 - 366

DOI: https://doi.org/10.13995/j.cnki.11-1802/ts.038843

Design and synthesis of stimulus responsive DNA hydrogel and its research progress in the field of food safety

  • ZHANG Hongpeng ,
  • XIE Gang ,
  • LI Kejing ,
  • LUO Fei ,
  • DOU Jinxin ,
  • ZHU Daoxing ,
  • GUO Yuyao ,
  • HAN Yitao
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  • 1(School of Healthy Science and Engineering, University of Shanghai for Science and Technology, Shanghai 200082, China)
    2(Academy of National Food and Strategic Reserves Administration, Beijing 100037, China)
    3(School of Food Science and Engineering, Wuhan Polytechnic University, Wuhan 430043, China)

Received date: 2024-02-06

  Revised date: 2024-02-26

  Online published: 2024-07-12

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Abstract

DNA hydrogel with three-dimensional network structure has been attracted much attention due to its biological characteristics of DNA and the skeleton function of hydrogel.According to its good stability and specific recognition ability, it can respond to a variety of signals and convert between gel and sol.It has been widely used in biosensing. This study focuses on the synthesis of DNA hydrogels, the types of stimulation signals, and their applications in the field of food safety.According to the different synthesis methods, it can be divided into physical and chemical synthesis methods, and according to the type of stimulus signal, it can be divided into temperature-responsive, pH-responsive, photon-responsive, biomolecular responsive and multi-responsive stimulus signal DNA hydrogels.The research progress of DNA hydrogel in the field of food safety for the detection of mycotoxins, heavy metal ions, foodborne pathogenic bacteria, antibiotic residues and illegal additives is summarized, and its development prospects are expounded.

Key words： DNA hydrogel; stimulus-responsive; biosensing; specific recognition; food safety

Cite this article

ZHANG Hongpeng , XIE Gang , LI Kejing , LUO Fei , DOU Jinxin , ZHU Daoxing , GUO Yuyao , HAN Yitao . Design and synthesis of stimulus responsive DNA hydrogel and its research progress in the field of food safety[J]. Food and Fermentation Industries, 2024 , 50(11) : 360 -366 . DOI: 10.13995/j.cnki.11-1802/ts.038843

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