Food and Fermentation Industries >

2024 , Vol. 50 >Issue 13: 263 - 269

DOI: https://doi.org/10.13995/j.cnki.11-1802/ts.036225

Evaluation of components and biological activities of Schisandra chinensis and Schisandra sphenanthera oil

  • HUANG Jiulin ,
  • LIU Wenwen ,
  • HAN Kemei ,
  • WANG Zhenzhen ,
  • WANG Ye ,
  • CHEN Shasha ,
  • HAN Yinyi
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  • 1(Department of Chemistry and Chemical Engineering, Ankang University, Ankang 725000, China)
    2(the Youth Innovation Team of Shaanxi Universities of Development and Utilization of Qinba Chinese Medicine Resources, Ankang 725000, China)
    3(Shaanxi Provincial University Engineering Research Center of Development and Utilization of Qinba Chinese Medicine Resources, Ankang 725000, China)

Received date: 2023-05-23

  Revised date: 2023-07-12

  Online published: 2024-08-02

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Abstract

This study aimed to investigate the volatile components and biological activities of Schisandra chinensis and Schisandra sphenanthera oil, which were extracted by supercritical CO2 fluid extraction from S.chinensis and S.sphenanthera.GC-MS and HPLC were used to analyze the components of S.chinensis and S.sphenanthera oil.The hypoglycemic activity was determined by the HepG2 cells insulin resistance model, and the antioxidant activity was measured by DPPH radical scavenging experiment.Results showed that the contents of schisandrin, schizandrin B, and fatty acids in S.chinensis extract were significantly higher than those of S.sphenanthera extract.The effect of S.sphenanthera extract on reducing insulin resistance was stronger than that of S.chinensis extraction.But it was the opposite result in the DPPH radical scavenging experiment.Therefore, the hypoglycemic effect of S.sphenanthera was better, while the antioxidant effect of S.chinensis was better.

Key words： Schisandra chinensis and Schisandra sphenanthera oil; component analysis; hypoglycemic activity; antioxidant activity

Cite this article

HUANG Jiulin , LIU Wenwen , HAN Kemei , WANG Zhenzhen , WANG Ye , CHEN Shasha , HAN Yinyi . Evaluation of components and biological activities of Schisandra chinensis and Schisandra sphenanthera oil[J]. Food and Fermentation Industries, 2024 , 50(13) : 263 -269 . DOI: 10.13995/j.cnki.11-1802/ts.036225

References

[1] 谭晓虹, 田嘉铭, 杨辉, 等.南五味子有效成分及其药理作用的研究进展[J].神经药理学报, 2014, 4(6):28-32.
TAN X H, TIAN J M, YANG H, et al.Research progress on chemical constituents in Schisandra sphenanthera Rehd.et Wils.and its pharmacological activities[J].Acta Neuropharmacologica, 2014, 4(6):28-32.
[2] 马嘉慕, 刘晓云, 任雪阳, 等.基于AHP-SOM聚类-TOPSIS的白及保胃护肝保健食品配方设计与评价[J].中草药, 2021, 52(18):5676-5687.
MA J M, LIU X Y, REN X Y, et al.Formula design and evaluation of health food with protection of gastric mucosa and liver of Bletillae Rhizoma based on AHP-SOM-TOPSIS algorithm[J].Chinese Traditional and Herbal Drugs, 2021, 52(18):5676-5687.
[3] 国家药典委员会. 中华人民共和国药典(一部)[M].北京:中国医药科技出版社, 2010, 65.
Chinese Pharmacopoeia Commission.Pharmacopoeia of People's Repubic of China (Vol I) [M].Beijing:China Medical Science Press, 2020, 65.
[4] 王卫明, 刘亮, 彭慧, 等.南五味子和五味子的基原考证和现代研究[J].中华中医药杂志, 2019, 34(7):3220-3223.
WANG W M, LIU L, PENG H, et al.Textual research and modern research of Schisandrae sphenantherae Fructus and Schisandrae chinensis Fructus[J].China Journal of Traditional Chinese Medicine and Pharmacy, 2019, 34(7):3220-3223.
[5] 邢楠楠, 屈怀东, 任伟超, 等.五味子主要化学成分及现代药理作用研究进展[J].中国实验方剂学杂志, 2021, 27(15):210-218.
XING N N,QU H D,REN W C, et al.Main chemical constituents and modern pharmacological action of Schisandrae chinensis Fructus:A review[J].Chinese Journal of Experimental Traditional Medical Formulae, 2021, 27(15):210-218.
[6] 李晓博, 胡文忠, 李婧, 等.五味子果实的功能作用及主要活性成分研究进展[J].食品工业科技, 2016, 37(4):386-390.
LI X B,HU W Z,LI J,et al.Review on the extraction of main effective active ingredients and function of Schisandra chinensis(Turcz.)Baill[J].Science and Technology of Food Industry, 2016, 37(4):386-390.
[7] 张明晓, 黄国英, 白羽琦, 等.南、北五味子的化学成分及其保肝作用的研究进展[J].中国中药杂志, 2021, 46(5):1017-1025.
ZHANG M X, HUANG G Y, BAI Y Q, et al.Research advances in chemical constituents and hepatoprotective effect of Schisandrae sphenantherae Fructus and Schisandrae chinensis Fructus[J].China Journal of Chinese Materia Medica, 2021, 46(5):1017-1025.
[8] 梁华, 彭博伟, 王燕, 等.五味子有效成分的降糖作用及机制研究探析[J].辽宁中医药大学学报, 2021, 23(8):1-5.
LIANG H, PENG B W, WANG Y, et al.Research analysis of hypoglycemic effect and mechanism of Wuweizi (Schisandre chinensis fructus) active components[J].Journal of Liaoning University of Traditional Chinese Medicine, 2021, 23(8):1-5.
[9] JIN D, ZHAO T, FENG W W, et al.Schisandra polysaccharide increased glucose consumption by up-regulating the expression of GLUT-4[J].International Journal of Biological Macromolecules, 2016, 87:555-562.
[10] LI X K, LI M Y, DENG S, et al.A network pharmacology-integrated metabolomics strategy for clarifying the action mechanisms of Schisandrae chinensis Fructus for treating drug-induced liver injury by acetaminophen[J].Bioorganic & Medicinal Chemistry, 2021, 31:115992.
[11] CHEN X, CAO J H, SUN Y, et al.Ethanol extract of Schisandrae chinensis Fructus ameliorates the extent of experimentally induced atherosclerosis in rats by increasing antioxidant capacity and improving endothelial dysfunction[J].Pharmaceutical Biology, 2018, 56(1):612-619.
[12] LI N, LIU J L, WANG M Y, et al.Sedative and hypnotic effects of Schisandrin B through increasing GABA/Glu ratio and upregulating the expression of GABA A in mice and rats[J].Biomedicine & Pharmacotherapy, 2018, 103:509-516.
[13] YUAN R S, TAO X, LIANG S, et al.Protective effect of acidic polysaccharide from Schisandra chinensis on acute ethanol-induced liver injury through reducing CYP2E1-dependent oxidative stress[J].Biomedicine & Pharmacotherapy, 2018, 99:537-542.
[14] 张金朋, 郭晓帆, 杨园园, 等.UPLC同时测定五味子木脂素纯化物中15个化学成分的含量[J].药物分析杂志, 2022, 42(10):1697-1707.
ZHANG J P,GUO X F,YANG Y Y,et al.Simultaneous determination of fifteen components in purified lignans from Schisandrae chinensis Fructus by UPLC[J].Chinese Journal of Pharmaceutical Analysis, 2022, 42(10):1697-1707.
[15] 刘子祯, 姜蕊, 许冬瑾.醋五味子配方颗粒的特征图谱建立及5种成分的含量测定[J].中国药房, 2021, 32(12):1453-1459.
LIU Z Z,JIANG R,XU D J.Establishment of characteristic pattern of vinegar-processed Schisandra chinensis formula granules and content determination of 5 components[J].China Pharmacy, 2021, 32(12):1453-1459.
[16] 郭良君, 郑巍, 王翔, 等.不同产地南五味子和北五味子中2种三萜酸的含量测定[J].第二军医大学学报, 2021, 42(1):107-111.
GUO L J, ZHENG W, WANG X, et al.Determination of two triterpenoid acids in Schisandra sphenanthera and Schisandra chinensis from different habitats[J].Academic Journal of Second Military Medical University, 2021, 42(1):107-111.
[17] 陈舒妤, 石婧婧, 邹立思, 等.UFLC-Q-TRAP-MS/MS同时测定五味子中木脂素及有机酸类成分[J].中国中药杂志, 2018, 43(10):2104-2111.
CHEN S Y, SHI J J, ZOU L S, et al.Simultaneous determination of lignans and organic acids in Schisandrae chinensis Fructus by UFLC-Q-TRAP-MS/MS[J].China Journal of Chinese Materia Medica, 2018, 43(10):2104-2111.
[18] 董家潇, 郑巍, 孙亮, 等.北五味子果实低极性化学成分的GC-MS分析[J].解放军药学学报, 2017, 33(5):391-395.
DONG J X, ZHENG W, SUN L, et al.GC-MS analysis of low-polarity components from fruits of Schisandra chinensis(Turcz.)Baill[J].Pharmaceutical Journal of Chinese PLA, 2017, 33(5):391-395.
[19] 刘亚敏, 刘玉民, 李鹏霞.超临界CO2流体萃取-GC-MS分析南北五味子挥发油成分[J].食品科学, 2011, 32(6):204-208.
LIU Y M,LIU Y M,LI P X.Composition analysis of volatile oils from Schisandra spenanthera Rehd.et Wils.and Schisandra chinensis (Turcz) Baill.by supercritical CO2fluid extraction and GC-MS[J].Food Science, 2011, 32(6):204-208.
[20] 谢旭东, 穆淑珍, 沈晓华, 等.北五味子总木脂素的GC-MS分析及其生物活性[J].中国实验方剂学杂志, 2016, 22(2):33-37.
XIE X D, MU S Z, SHEN X H, et al.GC-MS analysis and bioactivity of total lignans from Schisandrae chinensis Fructus[J].Chinese Journal of Experimental Traditional Medical Formulae, 2016, 22(2):33-37.
[21] 李昕, 聂晶, 高正德, 等.超声微波协同水蒸气蒸馏-GC-MS分析南、北五味子挥发油化学成分[J].食品科学, 2014, 35(8):269-274.
LI X, NIE J, GAO Z D, et al.Analysis of volatile oils from fruits of Schisandra chinensis (Turcz.) Baill and Schisandra sphenanthera Rehd.et Wils.by ultrasonic-microwave assisted steam distillation coupled with gas chromatography-mass spectrometry[J].Food Science, 2014, 35(8):269-274.
[22] 魏斌斌, 陈晓辉, 苏丹, 等.北五味子油中五味子甲素与五味子乙素的RP-HPLC测定[J].药物分析杂志, 2009, 29(12):2061-2063.
WEI B B, CHEN X H, SU D, et al.RP-HPLC determination of deoxyschizandrin and γ-schizandrin in Schisandra chinensis (Turcz.) Baill.oil[J].Chinese Journal of Pharmaceutical Analysis, 2009, 29(12):2061-2063.
[23] 向智敏, 李会林, 张骊.五味子超临界CO2提取物的气相色谱质谱分析[J].色谱, 2003, 21(6):568-571.
XIANG Z M, LI H L, ZHANG L.Study on supercritical carbon dioxide extract from Schisandra chinensis by gas chromatography-mass spectrometry[J].Chinese Journal of Chromatography, 2003, 21(6):568-571.
[24] 程振玉, 杨英杰, 刘治刚, 等.高效液相色谱法测定北五味子中5种木脂素含量[J].理化检验(化学分册), 2014, 50(5):575-578.
CHENG Z Y YANG Y J, LIU Z G, et al.HPLC determination of 5 lignans in Schisandra chinensis (Turcz.) Baill[J].Physical Testing and Chemical Analysis(Part B:Chemical Analysis),2014, 50(5):575-578.
[25] 费烨, 王雍, 龚仕英, 等.苦荞清蛋白酶解物对高糖诱导的HepG2细胞胰岛素抵抗的保护作用[J].食品科学, 2021, 42(1):222-227.
FEI Y, WANG Y, GONG S Y, et al.Protective effect of Tartary buckwheat albumin hydrolysate on high glucose induced insulin resistance in HepG2 cells[J].Food Science, 2021, 42(1):222-227.
[26] 李启思, 王雅玲, 邓玉华, 等.五味子木脂素超声提取工艺优化及其抗氧化和抗真菌的潜力[J].浙江农业学报, 2021, 33(11):2145-2154.
LI Q S, WANG Y L, DENG Y H,et al.Optimization of ultrasonic extraction technology of Shisandra lignans and its anti-oxidant and anti-fungi potentials[J].Acta Agriculturae Zhejiangensis, 2021, 33(11):2145-2154.
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