Researchprogress on antibacterial structure-activity relationship, antibacterial mechanism and application in food of plant-derived active substances

  • YANG Mingchen ,
  • HU Feng ,
  • FU Jiangyan ,
  • FU Liang ,
  • CHEN Yongsheng
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  • 1(Department of Food Science and Engineering, Jinan University, Guangzhou 510000, China)
    2(Guangdong Chubang Food Co., Ltd., Yangjiang 529800, China)

Received date: 2023-09-27

  Revised date: 2023-12-07

  Online published: 2024-10-14

Abstract

Plants possesses a wide array of natural antibacterial components with complex and diverse molecular structures that enable multifaceted antibacterial mechanism.Among which, they are categorized by type and include polysaccharides, polyphenols, alkaloids, terpenoids and others.Investigations of these plant-derived antibacterial compounds have become paramount in biomedical sciences due to their unique characteristics such as low drug resistances, potent antibacterial activities and broad-spectrum efficacies.Their primary antibacterial mechanism involves disrupting bacterial cell structures, regulating gene expressions, inhibiting metabolic activities, modulating cell membrane potentials and more.This review provided comprehensive overviews of natural antibacterial substances found from both domestic and international plants.Analysis was also conducted on their classifications, structure-activity relationships, antibacterial mechanisms and potential applications in medicine, food and chemical industries.The goal of this review is to provide robust theoretical foundations and innovative insights to practically implement natural antibacterial substances for advancing biomedicine and pharmaceuticals.

Cite this article

YANG Mingchen , HU Feng , FU Jiangyan , FU Liang , CHEN Yongsheng . Researchprogress on antibacterial structure-activity relationship, antibacterial mechanism and application in food of plant-derived active substances[J]. Food and Fermentation Industries, 2024 , 50(18) : 367 -374 . DOI: 10.13995/j.cnki.11-1802/ts.037500

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