To explore the effects of soybean protein isolate (SPI) on monacolin K (MK) and Monascus pigments (MPs) production by three strains of M.pilosus and one strain of M.ruber, the yields and homologues of MPs and MK produced by the aforementioned Monascus strains were investigated in solid and liquid states fermentation by UV spectrophotometry and HPLC.The results indicated that the red MPs production by M.ruber MJ-1 was increased by 4.59 times, the MPs yields of M.pilosus MS-1 and M.pilosus YDJ-1 were significantly inhibited, and the MK production of three Monascus pilosus strains were enhanced, when 1% SPI were used in solid-state fermentation (P<0.05).The yields of red, orange and yellow MPs produced by M.ruber MJ-1 and M.pilosus YDJ-1 were improved respectively, and the MK production of M.pilosus YDJ-2 was increased by 0.88 times (P<0.05), when 1% SPI was used in PDB medium.In the synthetic medium with 1% SPI, the yields of MPs with three colors produced by M.ruber MJ-1 and M.pilosus YDJ-1 were increased, respectively, and the MPs production by M.pilosus MS-1 was significantly inhibited (P<0.05).Moreover, the MK yields of M.pilosus MS-1 and M.pilosus YDJ-1 were promoted by 0.95 and 1.15 times, respectively (P<0.05).The results can provide a reference for regulating the selective production of MPs or MK by SPI.
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