This research aims to use self-made biomass sugar for fermentation and establish a bio-based glycolic acid and polyglycolic acid production process through systematic separation and purification research.Finally, using deep eutectic solvent treatment, the concentration of corncob hydrolyzed glucose solution reached 148.05 g/L, and the conversion rate reached 93.10%.The yield of glycolic acid in a 5 L tank reached 49.80 g/L, which was 16.00% higher than using glucose.Through systematic research on separation and purification processes such as calcification, acidification, and crystallization, the recovery rate of glycolic acid reached 87.50%.The purity of glycolic acid crystals reached 99.50%, meeting the standards for high-grade commercial products.Polymerization was carried out using azeotropic distillation method, and the product was confirmed to be polyglycolic acid with a high crystallinity of 89.60% by infrared, nuclear magnetic resonance and X-ray diffraction.The above results have laid the foundation for the industrial production of bio-based glycolic acid and its polymers.
YANG Guang
,
MAO Yin
,
LI Guohui
,
ZHAO Yunying
,
DENG Yu
. Research on synthesis of bio-based glycolic acid and polyglycolic acid[J]. Food and Fermentation Industries, 2025
, 51(4)
: 20
-27
.
DOI: 10.13995/j.cnki.11-1802/ts.038409
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