Food and Fermentation Industries >

2025 , Vol. 51 >Issue 16: 351 - 362

DOI: https://doi.org/10.13995/j.cnki.11-1802/ts.041838

Differences in basic nutrients and metabolites in three types of Lycium chinense in Tibet

  • FENG Zongtao ,
  • TIAN Mengle ,
  • MAIDINA Paerhati ,
  • YIN Xiu ,
  • LAN Xiaozhong ,
  • LU Yazhou
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  • 1(Food Science College, Xizang Agriculture and Animal Husbandry University, Linzhi 860000, China)
    2(The Provincial and Ministerial Co-founded Collaborative Innovation Center for R&D in Tibet Characteristic Agricultural and Animal Husbandry Resources, Xizang Agriculture and Animal Husbandry University, Linzhi 860000, China)
    3(Key Laboratory of Tibetan Medicine Resources Conservation and Utilization of Tibet Autonomous Region, Xizang Agriculture and Animal Husbandry University, Linzhi 860000, China)

Received date: 2024-12-12

  Revised date: 2025-01-09

  Online published: 2025-08-29

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Abstract

To explore the variations in the metabolites in three types of Lycium chinense produced in Tibet, the metabolic characteristics were analyzed using non-targeted metabolomics combined with multivariate statistical and pathway enrichment analysis.Results showed that the Lycium barbarum grown in Rikaze had the highest contents of total sugar, polysaccharides, protein, and phenols, while Lycium ruthenicum from Rikaze had the contents of vitamin B1, vitamin C, and total flavonoids.Lycium amarum was the only one to achieve the optimal protein level (42.95%).A total of 1 142 differential metabolites were screened using differential metabolite analysis, including 787, 765, and 755 differential metabolites in L.amarum vs L.ruthenicum, L.amarum vs L.barbarum, and L.barbarum vs L.ruthenicum, respectively.Metabolic pathway enrichment analysis showed that the differential metabolites of the three L.chinense were mainly enriched in linoleic acid metabolism, α-linolenic acid metabolism, tricarboxylic acid cycle, ascorbic acid, and arabic acid metabolism.A total of 108 metabolites contributed significantly to the sample based on the screening criteria of variable important in projection value >1, |log2FC|≥1, and false discovery rate <0.05, of these, the relative abundance of lipids and lipid molecules, phenylpropanoids, polyketones, and organic oxide compounds were higher, and the γ-linolenic acid, cryptochlorogenic acid, rutin, quercetin, and kukoamine B could be the key metabolites to distinguish between different L.chinense produced in Xizang.The metabolic characteristics and differences in three types of L.chinense cultivated in Xizang were preliminarily clarified, which could provide a certain scientific basis for future processing, utilization, and extraction of active substances.

Key words： Lycium barbarum; Lycium ruthenicum; Lycium amarum; non-targeted metabolomics approach; differential metabolites

Cite this article

FENG Zongtao , TIAN Mengle , MAIDINA Paerhati , YIN Xiu , LAN Xiaozhong , LU Yazhou . Differences in basic nutrients and metabolites in three types of Lycium chinense in Tibet[J]. Food and Fermentation Industries, 2025 , 51(16) : 351 -362 . DOI: 10.13995/j.cnki.11-1802/ts.041838

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