Food and Fermentation Industries >

2025 , Vol. 51 >Issue 23: 219 - 226

DOI: https://doi.org/10.13995/j.cnki.11-1802/ts.042425

Preparation and characterization of a novel zinc supplement based on hyperbranched β-glucan

  • LI Cui ,
  • WEN Jiayi ,
  • XU Mengmeng ,
  • SHI Guiyang ,
  • CHEN Lei ,
  • DING Zhongyang
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  • 1(Key Laboratory of Carbohydrate Chemistry and Biotechnology of Ministry of Education, School of Biotechnology, Jiangnan University, Wuxi 214122, China)
    2(National Engineering Research Center of Cereal Fermentation and Food Biomanufacturing, Jiangnan University, Wuxi 214122, China)

Received date: 2025-02-19

  Revised date: 2025-04-17

  Online published: 2025-12-25

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Abstract

To develop a novel zinc-fortifying agent with enhanced digestibility and absorption, this study designed a hyperbranched polysaccharide-zinc chelate (PTR-HBG-Zn) using Pleurotus tuber-regium hyperbranched β-glucan (PTR-HBG) as the ligand.The preparation process was systematically optimized through single-factor experiments.The optimal conditions, including pH 6.0, 50 ℃, and 0.35 mol/L initial zinc sulfate concentration with 2 h reaction duration, yielded a chelate with a zinc content of (47.06±1.85) mg/g.Multidimensional characterization techniques including FTIR and XRD confirmed successful chelation and revealed conformational transitions in the polysaccharide chain conformation upon zinc binding.Rheological analysis and FESEM observations further demonstrated that zinc coordination induced gelation.In vitro simulated gastrointestinal digestion revealed that PTR-HBG-Zn exhibited significantly higher zinc dissolution rates (P<0.05) in the intestinal phase compared to zinc sulfate and zinc gluconate.These findings highlight the superior bioavailability and stability of PTR-HBG-Zn, providing both theoretical foundations and experimental evidence for developing advanced polysaccharide-based zinc supplements.

Key words： hyperbranched β-glucan; polysaccharide-Zn; Zn supplement; trace elements; bioavailability

Cite this article

LI Cui , WEN Jiayi , XU Mengmeng , SHI Guiyang , CHEN Lei , DING Zhongyang . Preparation and characterization of a novel zinc supplement based on hyperbranched β-glucan[J]. Food and Fermentation Industries, 2025 , 51(23) : 219 -226 . DOI: 10.13995/j.cnki.11-1802/ts.042425

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