Research progress on the stability, structural analysis and biological activity of food-derived peptides

  • ZHANG Mengyuan ,
  • ZHANG Xinxue ,
  • LIU Haoyu ,
  • LIN Lulu ,
  • TIAN Rongrong ,
  • LIU Wenying
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  • 1(Beijing Engineering Research Center of Protein and Functional Peptides, China National Research Institute of Food & Fermentation Industries Co.Ltd., Beijing 100015, China)
    2(Biological Medicine Department, Beijing City University, Beijing 100094, China)

Received date: 2025-05-06

  Revised date: 2025-07-25

  Online published: 2026-03-25

Abstract

Foodborne peptides are small, bioactive molecules derived from proteins through processes such as enzymatic hydrolysis and fermentation.These peptides exhibit a range of biological activities, including blood pressure reduction, antioxidant effects, and immune regulation.Their sources, preparation methods, and key functions have attracted growing research interest.The biological activities of these peptides are influenced by amino acid sequences and structural characteristics.Recent advancements in enhancing their bioavailability focus on improving digestive stability and transmembrane absorption efficiency.Future research should prioritize efficient preparation methods, mechanisms of action, and safety assessments.Integrating multi-omics approaches with both in vivo and in vitro functional validations is expected to elucidate structure-function relationships and promote the application of foodborne peptides in functional foods and medical fields.

Cite this article

ZHANG Mengyuan , ZHANG Xinxue , LIU Haoyu , LIN Lulu , TIAN Rongrong , LIU Wenying . Research progress on the stability, structural analysis and biological activity of food-derived peptides[J]. Food and Fermentation Industries, 2026 , 52(5) : 393 -402 . DOI: 10.13995/j.cnki.11-1802/ts.043211

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