Research on the formation pattern and main health functions of Gastrodia elata Blume health foods

  • JIA Fanfan ,
  • KANG Sirui ,
  • ZHANG Xiaorui ,
  • ZHAGN Bofeng ,
  • CHEN Chen
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  • 1(Qinba State Key Laboratory of Biological Resources and Ecological Environment (Incubation), College of Biological Science and Engineering, Shaanxi University of Technology, Hanzhong 723000, China)
    2(Shaanxi Hanwang Lueyang Traditional Chinese Medicine Technology Co.Ltd., Lueyang 724300, China)

Received date: 2025-04-09

  Revised date: 2025-08-22

  Online published: 2026-04-10

Abstract

This study aims to clarify the formulae of health food products containing Gastrodia elata Blume (G.elata) and the mechanism of its main health functions.Through the statistics of health food containing G.elata registered in the State Administration for Market Supervision and Administration, the basic information such as the year of approval, dosage form, health function and suitable/contraindicated groups were analysed, and frequency statistics and association rule analysis were also carried out.The main mechanisms of health functions exerted by G.elata health food products were also investigated through network pharmacology and molecular docking technology.As a result, a total of 136 health food products containing G.elata were collected, of which the largest number was in capsule form;11 health functions were involved, mainly helping to improve sleep, helping to enhance immunity, and helping to maintain a healthy level of blood pressure;a total of 96 traditional Chinese medicines (TCM) were involved in the composition of raw materials, with warmth and sweetness being the main ones;and 161 active ingredients and 1 037 targets of G.elata were obtained, which exerted their main health effects mainly through signaling pathways such as the interactions of neuroactive ligands and receptors, PI3K-AKT, HIF1 and other signaling pathways.Data mining and network pharmacology techniques can predict the formulation mode, health functions and potential action targets and mechanism of action of health food products containing G.elata, and provide a reference basis for the research and development of G.elata-related products.

Cite this article

JIA Fanfan , KANG Sirui , ZHANG Xiaorui , ZHAGN Bofeng , CHEN Chen . Research on the formation pattern and main health functions of Gastrodia elata Blume health foods[J]. Food and Fermentation Industries, 2026 , 52(6) : 192 -201 . DOI: 10.13995/j.cnki.11-1802/ts.042963

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