Research progress of Baijiu Daqu based on omics technology

  • LIU Chunli ,
  • XU Shugang ,
  • ZHANG Erkang ,
  • WEI Lulu ,
  • WEN Yong ,
  • REN Rong ,
  • CHEN Mingxue ,
  • HE Kaiping ,
  • CHENG Pingyan
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  • 1(Guizhou Xijiu Co.Ltd., Xishui 564600, China)
    2(College of Biotechnology, Jiangnan University, Wuxi 214122, China)

Received date: 2025-07-29

  Revised date: 2025-09-15

  Online published: 2026-06-03

Abstract

As the core saccharification and fermentation agent in Baijiu production, the complex fermentation mechanism of Daqu involving multi-species microbial metabolism has always been a key research topic in the Baijiu brewing field.In recent years, omics technologies have provided important support for analyzing the fermentation mechanism of Daqu with their high-throughput and systematic advantages.Focusing on the problems existing in the current Daqu research as the breakthrough point, this article systematically expounds the research progress of frontier omics technologies, such as amplicon sequencing, metagenomics, macrotranscriptomics, metaproteomics, and metabolomics in the analysis of the Daqu fermentation mechanism.At the same time, it expounds the integration advantages and typical application cases of multi-omics joint technology in the research of Daqu fermentation.Finally, this article deeply analyzes the challenges faced by current omics technologies in the research of Baijiu Daqu fermentation and looks forward to future research directions, aiming to provide theoretical references for promoting basic research and industrial technology innovation in Baijiu Daqu fermentation.

Cite this article

LIU Chunli , XU Shugang , ZHANG Erkang , WEI Lulu , WEN Yong , REN Rong , CHEN Mingxue , HE Kaiping , CHENG Pingyan . Research progress of Baijiu Daqu based on omics technology[J]. Food and Fermentation Industries, 2026 , 52(9) : 380 -391 . DOI: 10.13995/j.cnki.11-1802/ts.044062

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