Food and Fermentation Industries >

2026 , Vol. 52 >Issue 12: 204 - 211

DOI: https://doi.org/10.13995/j.cnki.11-1802/ts.044321

Preparation, characterization, and bioactivity study of Zhangliang ginger essential oil nanoliposomes

  • YIN Guoyou ,
  • XU Juannu ,
  • XU Chaojun ,
  • LI Xianan ,
  • SUN Jie ,
  • DUAN Yabin ,
  • MA Peifang
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  • 1(College of Life Science and Engineering, Henan University of Urban Construction, Pingdingshan 467036, China)
    2(Pingdingshan Academy of Agricultural Sciences, Pingdingshan 467000, China)

Received date: 2025-08-25

  Revised date: 2025-11-15

  Online published: 2026-07-17

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Abstract

To address the challenges of poor water solubility, high volatility, and instability of Zhangliang ginger essential oil, the prepared nanoliposomes were systematically evaluated for their in vitro antioxidant and antimicrobial activity.This study employed steam distillation to extract essential oil from Zhangliang ginger (E-O), then encapsulated into liposomes (E-L) using soybean lecithin and cholesterol as wall materials through the thin-film dispersion method.The morphology and physical properties of E-L were characterized, with parallel evaluations of its antioxidant and antimicrobial activities.The results demonstrated that under the optimal conditions of lecithin-to-cholesterol ratio (6∶1, mass ratio), ultrasonic power (300 W), sonication time (15 min), and essential oil loading (5 mg/mL), the encapsulation efficiency of E-L reached (41.53±0.02)%.E-L exhibited a mean particle size of 122.73 nm with a polydispersity index (PDI) of 0.25 and zeta potential of -35.07 mV, indicating a monodisperse size distribution, stable surface charge, and excellent colloidal stability suitable for functional applications.In addition, E-L exhibited excellent pH stability and storage stability, along with significant antioxidant capacity [DPPH free radical and ABTS cationic radical scavenging rates of (50.92±0.88)% and (53.82±0.10)%, respectively] and antimicrobial properties.In summary, E-L demonstrated excellent stability and functional performance, providing a promising delivery system for this bioactive extract and offering valuable insights for the development of ginger essential oil-based formulations.

Key words： Zhangliang ginger essential oil; liposome; characterization; antioxidant activity; antibacterial activity

Cite this article

YIN Guoyou , XU Juannu , XU Chaojun , LI Xianan , SUN Jie , DUAN Yabin , MA Peifang . Preparation, characterization, and bioactivity study of Zhangliang ginger essential oil nanoliposomes[J]. Food and Fermentation Industries, 2026 , 52(12) : 204 -211 . DOI: 10.13995/j.cnki.11-1802/ts.044321

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