Food and Fermentation Industries

Study on the Purification and Lowing Hyperlipidemia Activity of Fucoidan from Sargassum henslowianum

  • Chen Su-hua ,
  • Wang Wei-min ,
  • Liu Hui ,
  • Li Chun-lian ,
  • Liu Chen-ying
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Online published: 2010-05-25

Abstract

The Sulfated fucan(SPF) was extracted by ultrasonic extraction process from the Sargassum henslowianum,purified by ethanol,and then defatted,deproteinized to the primary fucoidan.The hyperlipidemia mice fed with purified primary fucoidan showed that: the hypolipidemia effect of the high,medium and low dose of fucoidan were all superior to the zhinbiticose.And the high dose was the best.The total cholesterol,low-density lipoprotein,triglyceride were all decreased significantly(P <0.01),and high-density lipoprotein was increased significantly(P <0.05) than the control group.Arteriosclerosic index,AI1 and AI2 was decreased significantly(P<0.01).The conclusion is that the Sulfated fucan from Sargassum henslowianum has obvious activity on lowing hyperlipidemia.

Cite this article

Chen Su-hua , Wang Wei-min , Liu Hui , Li Chun-lian , Liu Chen-ying . Study on the Purification and Lowing Hyperlipidemia Activity of Fucoidan from Sargassum henslowianum[J]. Food and Fermentation Industries, 2010 , 36(05) : 28 -31 . DOI: 10.13995/j.cnki.11-1802/ts.2010.05.039

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