To study the effects of Antibacterial and anti-oxidation of Extracts from Kadsura longipedunculata.The inhibition effect of the extracts from K.longipedunculata against E.coli,S.aureus,S.paratyphi and its scavenging abilities to 1,1-2-phenyl-2-bitter phenylhydrazine radical(DPPH·),hydroxyl radical(·OH),superoxide anion(O2-·)were respectively determined via agar plate diffusion method,DPPH· method and pyrogallol auto-oxidation method.The extracts from K.longipedunculata,with its inhibition zone diameters larger than 20mm,have strong inhibition effect to three kinds of food pathogenic bacteria:E.coli,S.aureus and S.paratyphi.Inhibition zone diameters of inhibition and MIC of ethanol extract against E.coli,S.aureus,S.paratyphi were 34.8 mm,28.6mm,23.2mm,0.1250g/mL,0.0313 g /mL,0.1250 g /mL respectively,and scavenging abilities to 1,1-2-phenyl-2-bitter phenylhydrazine radical(DPPH·),hydroxyl radical(·OH),superoxide anion(O2-·)were 0.69 mg/mL,0.78 mg/mL,0.57 mg/mL.Distilled water extract of K.longipedunculata and MIC against E.coli,S.aureus,S.paratyphi were 25.4 mm,23.0 mm,23.4 mm,0.125 0 g/mL,0.0625g /mL,0.1250 g /mL respectively and scavenging abilities of 1,1-2-phenyl-2-bitter phenylhydrazine radical(DPPH ·),hydroxyl radical(·OH),superoxide anion(O2-·)were 0.72 mg/mL,0.63 mg/mL,0.61 mg/mL.K.longipedunculata extract has strong anti-oxidation and inhibition effect to bacteria.