The static adsorption and desorption capacities of 12 kinds of macroporous adsorption resins and 6 kinds of cation exchange resins used for mulberry anthocyanins were compared.It was found that the best macroporous adsorption resin was LX-68 and the optimal cation exchange resin was D001on.Through the static and dynamic conditions optimization,the best purification conditions of mulberry red pigment used by LX-68 resin were: 0.991 Abs,pH 3,absorption velocity 8 BV/h,pH 2.and 80% of acidic ethanol as elution agents,elution velocity 1 BV/h.The pigment purified by LX-68 resin was a dark purple powder,the color value was 114.The anthocyanins content was 39.9%,and the recovery of anthocyanins was 91.5%.D001 resin's optimum purification conditions were: Abs of solution 1.411,pH 2 and 6 BV/h,and elution solvent pH 1,60% of acidic ethanol with 3 BV/h elution velocity.The pigment purified by D001 resin was a powder with color-value 65,anthocyanins content 24.1%,and the recovery of anthocyanins 67.6%.Both LX-68 resin and D001 resin presented good adsorption separation properties to mulberry anthocyanins.However,the LX-68 resin's separation effect was better than D001 resin.