The ursolic acid from Crataegus was extracted by β-CD-ethanol solution assisted with microwave.The yield of the ursolic acid was determined by UV-spectrophotometry.The optimum extraction conditions were investigated through orthogonal test according to single factor experiment.The optimum extraction conditions were: ethanol concentration 80%,microwave power 60%,extraction time 100 s,solid to liquid ratio of 1∶ 25 and the amount of crataegus: m(β-CD) 1∶ 1.Under the optimum conditions,the yield of ursolic acid was increased to 3.374 mg/g with the presence of β-CD.