Research progress on tolerance and pathogenic mechanism of foodborne Salmonella spp. in human gastrointestinal tract

  • DONG Xiaolu ,
  • QIN Xiaojie ,
  • LIU Yangtai ,
  • SUN Tianmei ,
  • LIU Hong ,
  • WANG Xiang ,
  • LI Zhuosi ,
  • DONG Qingli
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  • 1(School of Health Science and Engineering, University of Shanghai for Science and Technology, Shanghai 200093, China)
    2(Shanghai Municipal Center for Disease Control and Prevention, Shanghai 200336, China)

Received date: 2021-03-30

  Revised date: 2021-04-13

  Online published: 2022-01-21

Abstract

Foodborne Salmonella spp. will encounter a series of stress conditions that are not conducive to its survival after entering human gastrointestinal tract. Salmonella spp. that adapts to these conditions will cause human disease through the role of its own virulence factors. In this review, the tolerance mechanism of foodborne Salmonella spp. under the stress of gastric acid, bile and intestinal osmotic pressure is summarized, the process of its infection to the host and the mechanism of virulence factors are overviewed, in order to provide a theoretical reference for the research on the pathogenicity of foodborne Salmonella spp. after the combined action of various stress conditions in human gastrointestinal tract.

Cite this article

DONG Xiaolu , QIN Xiaojie , LIU Yangtai , SUN Tianmei , LIU Hong , WANG Xiang , LI Zhuosi , DONG Qingli . Research progress on tolerance and pathogenic mechanism of foodborne Salmonella spp. in human gastrointestinal tract[J]. Food and Fermentation Industries, 2021 , 47(24) : 286 -292 . DOI: 10.13995/j.cnki.11-1802/ts.027513

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