Research progress on plant polysaccharides against kidney injury and its mechanism
LIU Ting1,2,3,4, ZHOU Xin1,2,3,4, ZHAO Chao1,2,3,4, GONG Xiaojian1,2,3,4, CHEN Huaguo1,2,3,4*
1(Key Laboratory for Information System of Mountainous Areas and Protection of Ecological Environment,Guizhou Normal University,Guiyang 550001,China) 2(Collaborative Innovation Center for Karst Mountain Ecological Environmental Protection and Resource Utilization (Project of Education Department of Guizhou Province),Guizhou Normal University,Guiyang 550001,China) 3(Guizhou Engineering Laboratory for Quality Control & Evaluation Technology of Medicine,Guizhou Normal University,Guiyang 550001,China) 4(Research Center for Quality Control of Natural Medicine,Guizhou Normal University,Guiyang 550001,China.)
Abstract: As a kind of food resource, the plant polysaccharides have many beneficial effects on human body in the form of dietary fiber, and it is also an effective anti-kidney damage agent. At present, the prevention and treatment of kidney disease are mainly based on drugs. However, there are also research on the supplementary treatment of kidney diseases using health products and functional foods. In this review, the intervention effects of plant polysaccharides on diabetic kidney injury, ischemia-reperfusion kidney injury, heavy metal kidney injury, chemical kidney injury, and drug-induced kidney injury from the food point of view were briefly reviewed, and the mechanisms of polysaccharides against kidney injury from both direct and indirect aspects were mainly discussed. Finally, the research direction of plant polysaccharides against kidney damage have further prospected, so as to provide a reference for the development of functional foods for the treatment of kidney injury.
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