Abstract: Detection for PET/PE composite film was conducted by ultra high-performance liquid chromatography mass spectrometry (UPLC-MS/MS), and one primary aromatic amines (PAAs) Bis(4-aminophenyl) sulfide as well as two plastic additives erucamide (EAD) and antioxidant 2246 (AO2246) were detected. Then the migration of PET/PE and PET/AL/PE in composite films under 40 ℃/10 d and 70 ℃/2 h conditions immersed in three kinds of simulants (4% acetic acid, 10% and 95% ethanol) were carried out. The proposed method could simultaneously to determine 25 PAAs and EAD in ESI+ mode, and also to investigate AO2246 in ESI-mode. It was validated in terms of linearity, matrix effect error, detection and quantification limits, repeatability and intermediate precision. The quantitative method presented recoveries ranging from 82.7% to 119%, with a precision (RSD) lower than 12.5% for the 27 substances. Based on the experimental results, several conclusions were drawn as follows. Firstly, the species and amount of PAAs migrated at 40 ℃/10 d were higher than those at 70 ℃/2 h. And time was the main factor affecting PAAs’ migration and higher temperatures may lead to more PAAs released. Secondly, the migration of both PAAs could be effectively reduced by aluminum layer at a low temperature. Thirdly, the difference among the results in three kinds of simulants suggested that pH could also has an impact that acidic condition weakened PAAs’ migration. Last but not the least, the migration of EAD and AO2246 was lower than TTC safety threshold and national standard GB 9685 respectively. However, PAAs’ content could not meet the requirement of European Union standard, which indicates high safety risk.
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