Research progress on nutritional function and processing technology of black garlic
YE Miao1,2, LIU Chunfeng1,2, LI Ziyu1,2, NIU Chengtuo1,2, WANG Jinjing1,2, ZHENG Feiyun1,2, LI Qi1,2 *
1(School of Biotechnology,Jiangnan University,Wuxi 214122,China) 2(Key Laboratory of Industrial Biotechnology,Ministry of Education,Jiangnan University,Wuxi 214122,China)
Abstract: Black garlic is a kind of functional deep processing product made from garlic,which is formed naturally under the condition of high temperature and high humidity.In this paper,the changes of nutrients in the formation of black garlic,the biological function,processing technology and endophyte of black garlic are reviewed.Furthermore,the existing problems and future research directions of the black garlic industry are prospected,to provide theoretical reference for the deep exploitation of black garlic products and the healthy development of the black garlic industry.
叶淼,刘春凤,李梓语,等. 黑蒜的营养功能及其加工工艺研究进展[J]. 食品与发酵工业, 2022, 48(1): 292-300.
YE Miao,LIU Chunfeng,LI Ziyu,et al. Research progress on nutritional function and processing technology of black garlic[J]. Food and Fermentation Industries, 2022, 48(1): 292-300.
SHANG A,CAO S,XU X,et al.Bioactive compounds and biological functions of garlic(Allium sativum L.)[J].Foods,2019,8(7):246.
[2]
杜瑞雪,王丽丽,张畅,等.大蒜及黑蒜多糖含量测定和抗氧化活性研究[J].食品研究与开发,2019,40(18):120-124.DU R X,WANG L L,ZHANG C,et al.Studies on polysaccharide contents and antioxidant effect of garlic and black garlic[J].Food Research and Development,2019,40(18):120-124.
[3]
宁月宝,曾丽,张鹏翔,等.发酵黑蒜粗多糖成分提取及小鼠降血糖研究[J].黑龙江畜牧兽医,2016(16):178-180.NING Y B,ZENG L,ZHANG P X,et al.Extraction of crude polysaccharide from fermented black garlic and its hypoglycemic effect in mice[J].Heilongjiang Animal Science and Veterinary Medicine,2016(16):178-180.
[4]
杨延存,蔡甜甜,于海坤,等.黑蒜多糖的提取及其抗氧化性研究[J].现代食品,2018,5(10):177-181;184.YANG Y C,CAI T T,YU H K,et al.Study on Extraction and Antioxidation of Polysaccharides from Black Garlic[J].Modern Food,2018,5(10):177-181;184.
[5]
YUAN H,SUN L J,CHEN M,et al.The comparison of the contents of sugar,amadori,and heyns compounds in fresh and black garlic[J].Journal of Food Science,2016,81(7):C1662-C1668.
[6]
ZHANG Z S,LEI M M,LIU R et al.Evaluation of alliin,saccharide contents and antioxidant activities of black garlic during thermal processing[J].Journal of Food Biochemistry,2015,39(1):39-47.
[7]
BAE S E,CHO S Y,WON Y D,et al.Changes in S-allyl cysteine contents and physicochemical properties of black garlic during heat treatment[J].LWT-Food Science and Technology,2014,55(1):397-402.
[8]
LU X M,LI N Y,QIAO X G,et al.Composition analysis and antioxidant properties of black garlic extract[J].Journal of Food and Drug Analysis,2017,25(2):340-349.
[9]
LIANG T F,WEI F F,LU Y,et al.Comprehensive NMR analysis of compositional changes of black garlic during thermal processing[J].Journal of Agricultural and Food Chemistry,2015,63(2):683-691.
[10]
卢连登,周御,黄振荣,等.高效液相色谱法同时测定黑蒜中蒜氨酸、脱氧蒜氨酸及γ-谷氨酰半胱氨酸含量[J].东北农业大学学报,2020,51(7):36-43.LU L D,ZHOU Y,HUANG Z R,et al.Simultaneous determination of alliin,deoxyalliin and γ-glutamyl-L-cysteine in black garlic by HPLC[J].Journal of Northeast Agricultural University,2020,51(7):36-43.
[11]
KIM N Y,PARK M H,JANG E Y,et al.Volatile distribution in garlic(Allium sativum L.) by solid phase microextraction(SPME) with different processing conditions[J].Food Science and Biotechnology,2011,20(3):775-782.
[12]
KIM S H,JUNG E Y,KANG D H,et al.Physical stability,antioxidative properties,and photoprotective effects of a functionalized formulation containing black garlic extract[J].Journal of Photochemistry and Photobiology.B,Biology,2012,117:104-110.
[13]
KANG O J.Physicochemical characteristics of black garlic after different thermal processing steps[J].Preventive Nutrition and Food Science,2016,21(4):348-354.
[14]
CHOI I S,CHA H S,LEE Y S.Physicochemical and antioxidant properties of black garlic[J].Molecules(Basel,Switzerland),2014,19(10):16 811-16 823.
[15]
TOLEDANO MEDINA M Á,MERINAS-AMO T,FERNÁNDEZ-BEDMAR Z,et al.Physicochemical Characterization and Biological Activities of Black and White Garlic:In Vivo and In Vitro Assays[J].Foods,2019,8(6):220.
[16]
BAE S E,CHO S Y,WON Y D,et al.A comparative study of the different analytical methods for analysis of S-allyl cysteine in black garlic by HPLC[J].LWT-Food Science and Technology,2012,46(2):532-535.
[17]
KANG O J.Evaluation of melanoidins formed from black garlic after different thermal processing steps[J].Preventive Nutrition and Food Science,2016,21(4):398-405.
[18]
WU J F,LIU Y N,DOU Z S,et al.Black garlic melanoidins prevent obesity,reduce serum LPS levels and modulate the gut microbiota composition in high-fat diet-induced obese C57BL/6 J mice[J].Food & Function,2020,11(11):9 585-9 598.
[19]
ZHANG X Y,LI N Y,LU X M,et al.Effects of temperature on the quality of black garlic[J].Journal of the Science of Food and Agriculture,2016,96(7):2 366-2 372.
[20]
LI N Y,LU X M,PEI H B,et al.Effect of freezing pretreatment on the processing time and quality of black garlic[J].Journal of Food Process Engineering,2015,38:329-335.
[21]
LEE Y M,GWEON O C,SEO Y J,et al.Antioxidant effect of garlic and aged black garlic in animal model of type 2 diabetes mellitus[J].Nutr Res Pract,2009,3(2):156-161.
[22]
李岩,吕昌龙,桑力轩,等.黑大蒜提取物联合抗生素对金黄色葡萄球菌和大肠埃希菌的体外抗菌作用研究[J].微生物学杂志,2014,34(2):59-62.LI Y,LV C L,SANG L X,et al.Antibiotic activity in vitro of black garlic(Allium sativum var.nigrum) extracts combined with antibiotics against Staphylococcus aureus and Escherichia coli[J].Journal of Microbiology,2014,34(2):59-62.
[23]
KIM H K,CHOI Y W,LEE E N,et al.5-Hydroxymethylfurfural from black garlic extract prevents TNFα-induced monocytic cell adhesion to HUVECs by suppression of vascular cell adhesion molecule-1 expression,reactive oxygen species generation and NF-κB activation[J].Phytotherapy Research,2011,25(7):965-974.
[24]
RIED K,FRANK O R,STOCKS N P.Aged garlic extract lowers blood pressure in patients with treated but uncontrolled hypertension:A randomised controlled trial[J].Maturitas,2010,67(2):144-150.
[25]
JUNG Y M,LEE S H,LEE D S,et al.Fermented garlic protects diabetic,obese mice when fed a high-fat diet by antioxidant effects[J].Nutrition Research(New York,N.Y.),2011,31(5):387-396.
[26]
HA A W,YING T,KIM W K.The effects of black garlic(Allium satvium) extracts on lipid metabolism in rats fed a high fat diet[J].Nutrition Research and Practice,2015,9(1):30-36.
[27]
SI L,LIN R,JIA Y,et al.Lactobacillus bulgaricus improves antioxidant capacity of black garlic in the prevention of gestational diabetes mellitus:a randomized control trial[J].Bioscience Reports,2019,39(8).
[28]
WANG X,JIAO F,WANG Q W,et al.Aged black garlic extract induces inhibition of gastric cancer cell growth in vitro and in vivo[J].Molecular Medicine Reports,2012,5(1):66-72.
[29]
王鑫,杨柯,王园园,等.黑蒜水提液对小鼠肝癌H22移植性实体瘤的生长干预[J].中华中医药杂志,2011,26(10):2 405-2 407.WANG X,YANG K,WANG Y Y,et al.Inhibitory effects of extractive from aged black garlic on the growth of H22-implanted solid tumor in mice[J].China Journal of Traditional Chinese Medicine and Pharmacy,2011,26(10):2 405-2 407.
[30]
PARK C,PARK S,CHUNG Y H,et al.Induction of apoptosis by a hexane extract of aged black garlic in the human leukemic U937 cells[J].Nutrition Research and Practice,2014,8(2):132-137.
[31]
SHIN J H,LEE C W,OH S J,et al.Hepatoprotective effect of aged black garlic extract in rodents[J].Toxicological Research,2014,30(1):49-54.
[32]
KIM J H,YU S H,CHO Y J,et al.Preparation of S-allylcysteine-enriched black garlic juice and its antidiabetic effects in streptozotocin-induced insulin-deficient mice[J].Journal of Agricultural and Food Chemistry,2017,65(2):358-363.
[33]
冯永辉,王庆辉,王美茹,等.黑大蒜提取物对小鼠细胞免疫应答影响的初步探讨[J].中国免疫学杂志,2010,26(11):982-985.FENG Y H,WANG Q H,WANG M R,et al.Effects of black garlic extracts on the cellular immune response in mice[J].Chinese Journal of Immunology,2010,26(11):982-985.
[34]
AO X,YOO J S,ZHOU T X,et al.Effects of fermented garlic powder supplementation on growth performance,blood profiles and breast meat quality in broilers[J].Livestock Science,2011,141(1):85-89.
[35]
HERMAWATI E,SARI D C R,PARTADIREDJA G.The effects of black garlic ethanol extract on the spatial memory and estimated total number of pyramidal cells of the Hippocampus of monosodium glutamate-exposed adolescent male Wistar rats[J].Anatomical Science International,2015,90(4):275-286.
[36]
AMINUDDIN M,PARTADIREDJA G,SARI D C.The effects of black garlic(Allium sativum L.) ethanol extract on the estimated total number of Purkinje cells and motor coordination of male adolescent Wistar rats treated with monosodium glutamate[J].Anatomical Science International,2015,90(2):75-81.
[37]
李洋,李胜军,陈浏丹,等.黑大蒜提取物对小鼠过敏性哮喘的治疗作用[J].中华临床医师杂志(电子版),2012,6(10):2 640-2 643.LY Y,LI S J,CHEN L D,et al.Therapeutic effects of black garlic extracts on allergic asthma in model of mice[J].Chinese Journal of Clinicians(Electronic Edition),2012,6(10):2 640-2 643.
[38]
钟成,徐国娟,吴晓英,等.保压时间对黑蒜部分营养成分和抗氧化作用的影响[J].现代食品科技,2014,30(3):49-52;136.ZHONG C,XU G J,WU X Y,et al.Effect of dwell time on partial nutrients and antioxidant capacity of black garlic[J].Modern Food Science and Technology,2014,30(3):49-52;136.
[39]
赵雪晴,李嗣生,侯文博,等.不同预处理对黑蒜品质的影响[J].食品工业科技,2017,38(23):1-4.ZHAO X Q,LI S S,HOU W B,et al.Effects of different pretreatments on the quality of black garlic[J].Science and Technology of Food Industry,2017,38(23):1-4.
[40]
朱新鹏,全玉洁.微波预处理制备黑蒜工艺优化及品质比较[J].保鲜与加工,2020,20(1):160-164.ZHU X P,QUAN Y J.Process optimization and quality comparison of the black garlic prepared by microwave pretreatment[J].Storage and Process,2020,20(1):160-164.
[41]
罗仓学,苏东霞,陈树雨.液态黑蒜发酵工艺优化[J].农业工程学报,2013,29(18):292-297.LUO C X,SU D X,CHEN S Y.Optimization of liquid-fermentation technology for black garlic[J].Transactions of the Chinese Society of Agricultural Engineering,2013,29(18):292-297.
[42]
PARK B M,CHA S A,KIM H Y,et al.Fermented garlic extract decreases blood pressure through nitrite and sGC-cGMP-PKG pathway in spontaneously hypertensive rats[J].Journal of Functional Foods,2016,22:156-165.
[43]
GU F L,CHEN Y G,FANG Y M,et al.Contribution of Bacillus isolates to the flavor profiles of Vanilla beans assessed through aroma analysis and chemometrics[J].Molecules(Basel,Switzerland),2015,20(10):18 422-18 436.
[44]
SEO H S,LEE S,SINGH D,et al.Evaluating the headspace volatolome,primary metabolites,and aroma characteristics of koji fermented with Bacillus amyloliquefaciens and Aspergillus oryzae[J].Journal of Microbiology and Biotechnology,2018,28(8):1 260-1 269.
[45]
SLATTERY C,COTTER P D,O’TOOLE P W.Analysis of health benefits conferred by Lactobacillus species from kefir[J].Nutrients,2019,11(6):1252.
[46]
姬妍茹,石杰,刘宇峰,等.黑蒜生产过程中大蒜内生菌的分离鉴定[J].农产品加工(上半月),2015(12):42-45;48.JI Y R,SHI J,LIU Y F,et al.Separation and Identification of Endophytic Bacteria Strains of Garlic During the Production of Black Garlic[J].Farm Products Processing,2015(12):42-45;48.
[47]
姬妍茹,刘玉,杨庆丽,等.一株产黑色素黑蒜发酵菌的分离与鉴定[J].食品科学技术学报,2017,35(1):59-63.JI Y R,LIU Y,YANG Q L,et al.Solation and identification of melanin producing bacteria from fermented black garlic[J].Journal of Food Science and Technology,2017,35(1):59-63.
[48]
QIU Z C,LU X M,LI N Y,et al.Characterization of garlic endophytes isolated from the black garlic processing[J].MicrobiologyOpen,2018,7(1):e547.
[49]
QIU Z C,LI N Y,LU X M,et al.Characterization of microbial community structure and metabolic potential using Illumina MiSeq platform during the black garlic processing[J].Food Research International,2018,106:428-438.