Abstract: To discover the effect of probiotic beverage on relieving diarrhea induced by Salmonellaparatyphi A and explore its mechanism, the diarrhea model mice were fed with probiotic beverage fermented by Lactobacillusacidophilus and Bifidobacterium animalis subsp. lactis. The diarrhea occurrence of mice was observed, and the count of Lactobacillusacidophilus and B. animalis subsp. lactis in feces were detected. The normal mice fed with the probiotics beverage and powder were intended to explore whether the probiotics have intestinal colonization effect. The count of L.acidophilus and B. animalis subsp. lactis in feces and intestinal tract were detected. The results showed that the diarrhea model mice in the experimental group fed with probiotic beverage stopped diarrhea after 1 d, and recovered faster than those in the control group. No watery stools and diarrhea showed up in mice which were fed with S.paratyphi A and probiotics beverage. The count of probiotics in feces after 5 d was similar to the control group. The amount of Lactobacillusacidophilus and B. animalis subsp. lactis in the intestinal tract of mice increased with the feeding time. The results suggested that by means of probiotic competition inhibition and colonization of the intestinal tract, probiotic beverage can relieve the diarrhea symptoms caused by S. paratyphi A in mice, and protect the intestinal tract as well.
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2022, Vol. 48 
