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食品与发酵工业  2020, Vol. 46 Issue (22): 270-275    DOI: 10.13995/j.cnki.11-1802/ts.024402
  综述与专题评论 本期目录 | 过刊浏览 | 高级检索 |
益生菌的生理功能及作用机理研究进展
阿热爱·巴合提1,2, 武瑞赟2, 肖梦圆2, 李平兰2, 谭春明2*
1(新疆维吾尔自治区产品质量监督检验研究院,新疆 乌鲁木齐,830013);
2(中国农业大学 食品科学营养工程学院,北京食品营养与人类健康高精尖创新中心,北京,100083)
Research progress in physiological function and mechanism of probiotics
AREAI Bahati1,2, WU Ruiyun2, XIAO Mengyuan2, LI Pinglan2, TAN Chunming2*
1(Xinjiang Uygur Autonomous Region Product Quality Supervision and Inspection Institute,Urumqi 830013,China);
2(College of Food Science and Nutritional Engineering,China Agricultural University,Beijing Advanced Innovation Center for Food Nutrition and Human Health,Beijing 100083,China)
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摘要 益生菌是一类人或动物的微生态调节剂,具有抗菌、改善肠道环境、降血脂、抗肿瘤及参与免疫调节等生理作用,具有潜在的应用价值和重要的理论意义。益生菌在防治某些疾病或保障人畜健康方面发挥着越来越重要的作用,其发挥作用的机制有增强肠道黏膜屏障功能、阻止病原菌的黏附和定植、增强系统的免疫反应及分泌物质和改变肠道环境。该文对益生菌的生理特性、功能及作用机理等方面进行了综述,并对其存在的问题及今后进一步的开发利用进行展望。
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阿热爱·巴合提
武瑞赟
肖梦圆
李平兰
谭春明
关键词:  益生菌  黏膜屏障  免疫调节  作用机理    
Abstract: Probiotics is a kind of microecological regulator of human or animal,which has the physiological functions of antibacterial,improving intestinal environment,reducing blood fat,antitumor and participating in immune regulation,and has potential application value and important theoretical significance.Probiotics play an increasingly important role in the protection of human and animal health or in the prevention and treatment of some diseases.Its mechanism is to strengthen the intestinal mucosal barrier function,prevent the adhesion and colonization of pathogenic bacteria,enhance the immune response of the system,secrete substances and change the intestinal environment.In this paper,the physiological characteristics,functions and mechanism of probiotics were reviewed,and the existing problems,future development and utilization of probiotics were prospected.
Key words:  probiotics    mucosal barrier    immunoregulation    mechanisms
收稿日期:  2020-05-11      修回日期:  2020-05-29           出版日期:  2020-11-25      发布日期:  2020-12-11      期的出版日期:  2020-11-25
基金资助: 国家自然科学基金面上项目(31671831)
作者简介:  本科,工程师(谭春明博士为通讯作者,E-mail:cmtan_ouc@163.com)
引用本文:    
阿热爱·巴合提,武瑞赟,肖梦圆,等. 益生菌的生理功能及作用机理研究进展[J]. 食品与发酵工业, 2020, 46(22): 270-275.
AREAI Bahati,WU Ruiyun,XIAO Mengyuan,et al. Research progress in physiological function and mechanism of probiotics[J]. Food and Fermentation Industries, 2020, 46(22): 270-275.
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http://sf1970.cnif.cn/CN/10.13995/j.cnki.11-1802/ts.024402  或          http://sf1970.cnif.cn/CN/Y2020/V46/I22/270
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