由于反应条件温和、选择性高、安全环保，酶法合成单脂肪酸甘油酯近年来受到了科学家们的广泛关注。单脂肪酸甘油酯的酶法合成工艺关键在于反应过程中酶活性的保持以及反应底物的混溶性，即酶催化反应体系的选择与调控。重点介绍了常见的酶催化反应体系在酶法合成单脂肪酸甘油酯中的应用研究进展，主要包括有机溶剂体系、反胶束体系、无溶剂体系、超临界流体体系和离子液体体系等。最后，对酶法合成单脂肪酸甘油酯的反应体系作了总结和展望。

Lipase-catalyzed synthesis of fatty acid monoglycerides has obtained a lot of research interests in recent years, since its mild reaction conditions, high selectivity, safe and environmentally friendly. The key to the enzymatic synthesis of fatty acid monoglycerides is the maintenance of enzyme activity and the miscibility of the reaction substrates during the reaction, that is, the selection and regulation of the enzymatic reaction system. The research progress on several enzymatic reaction systems of enzymatic synthesis of fatty acid monoglycerides is mainly introduced, such as organic solvent system, reverse micellar system, solvent-free system, supercritical fluid system and ionic liquid system. Finally, the advantages and disadvantages of aforementioned enzymatic reaction systems were summarized and forecasted.