以盾叶薯蓣为原料,研究了硫酸水解法生产薯蓣皂苷元的工艺。考察了硫酸水解时间、硫酸用量、索氏提取时间和硫酸浓度对薯蓣皂苷硫酸水解的影响,通过正交实验优化了工艺。结果表明,硫酸水解的最佳条件为:硫酸水解时间为4 h,硫酸用量为20 mL,索氏提取时间为6 h,硫酸浓度为1.5 mol/L。该工艺能获得皂苷元得率为3.762%,且酸污染少。

The produce technology of diosgenin extraction by sulfuric acid hydrolysis was studied with Dioscorea zingiberensis C H Wright as the raw material.Effects of sulfuric acid hydrolysis time,usage of sulfuric acid,Soxhlet extraction time and concentration of sulfuric acid on the sulfuric acid hydrolysis of dioscin were investigated.Optimized process by orthogonal experiments was obtained as: sulfuric acid hydrolysis 20mL for 4h,Soxhlet extraction 6h,sulfuric acid concentration at 1.5mol/L.Under the above conditions,the yield of diosgenin was up to 3.762%,acid pollution was reduced.The result provides a method to solve the existing problems in the diosgenin industrial.