为了增强卵磷脂的抗氧化性能和水溶性,解决卵磷脂因存在稳定性差,不易溶于水等缺点而无法得到广泛应用的难题,通过将β-环糊精对卵磷脂进行包络,制备了卵磷脂-β-环糊精包络物,并用红外光谱和差热分析对包络产物进行了表征并检测了包络物的体内抗氧化活性。研究结果表明,用卵磷脂-β-环糊精包络物对小白鼠实施灌胃,能有效地降低小鼠肝脏中丙二醛(MDA)的含量,提高超氧化物歧化酶(SOD)和谷胱甘肽过氧化物酶(GSH-PX)的活性。
To improve the antioxidation ability and water-solubility of phosphatidylcholine,phosphatidylcholine was inclusion with β-cyclodextrin.The antioxidative activity of phosphatidylcholine-β-cyclodextrin was studied and analyzed by infrared spectrum and athermalization.The results showed that after mice administered intragastrically with phosphatidylcholine-β-cyclodextrin,the level of MDA was reduced and the activities of SOD and GSH-PX were increased in liver.
