食品与发酵工业 >

2020 , Vol. 46 >Issue 21: 262 - 271

DOI: https://doi.org/10.13995/j.cnki.11-1802/ts.024540

综述与专题评论

海藻抗肿瘤活性肽的研究进展

  • 杨贤庆 ,
  • 刘晶 ,
  • 胡晓 ,
  • 陈胜军 ,
  • 吴燕燕 ,
  • 李来好 ,
  • 戚勃 ,
  • 邓建朝 ,
  • 杨莉莉
展开
  • 1(中国水产科学研究院南海水产研究所,国家水产品加工技术研发中心,农业农村部水产品加工重点实验室,广东 广州,510300);
    2(上海海洋大学 食品学院,上海,201306);
    3(广东百维生物科技有限公司,广东 化州,525100)
学士,二级研究员(通讯作者,E-mail:yxqgd@163.com)

收稿日期: 2020-05-25

  修回日期: 2020-06-17

  网络出版日期: 2020-12-11

基金资助

现代农业产业技术体系建设专项(CARS-50);广东省现代农业产业技术体系创新团队建设专项资金(项目编号:2019KJ151);农业农村部水产品加工重点实验室开放基金项目(NYJG201706);广东省海洋与渔业发展专项资金(技术推广)项目(2017A0001);国家水产品质量安全风险评估专项(GJFP201800904)

收起

Research progress on antitumor active peptides derived from seaweed

  • YANG Xianqing ,
  • LIU Jing ,
  • HU Xiao ,
  • CHEN Shengjun ,
  • WU Yanyan ,
  • LI Laihao ,
  • QI Bo ,
  • DENG Jianchao ,
  • YANG Lili
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  • 1(Key Laboratory of Aquatic Product Processing,Ministry of Agriculture and Rural Affairs;National Research and Development Center for Aquatic Product Processing; South China Sea Fisheries Research Institute,Chinese Academy of Fishery Sciences,Guangzhou 510300,China);
    2(College of Food Science and Technology,Shanghai Ocean University, Shanghai 201306,China);
    3(Guangdong Baiwei Bio Material Co.,Ltd,Huazhou 525100,China)

Received date: 2020-05-25

  Revised date: 2020-06-17

  Online published: 2020-12-11

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摘要

肿瘤是人类健康安全的严重威胁,发病率和死亡率逐年攀升。近年来,天然海藻成为获取高效、低毒副作用的生物活性肽的海洋生物来源之一,海藻源活性肽的抗肿瘤活性逐渐为研究人员所关注。文中综述了海藻活性肽的常见种类和常用制备方法,同时对海藻抗肿瘤活性肽的活性评价方法和作用机制加以阐述,期望为抗肿瘤天然药物和食品的开发提供参考。

关键词： 海藻; 抗肿瘤活性肽; 活性评价; 作用机制

本文引用格式

杨贤庆 , 刘晶 , 胡晓 , 陈胜军 , 吴燕燕 , 李来好 , 戚勃 , 邓建朝 , 杨莉莉 . 海藻抗肿瘤活性肽的研究进展[J]. 食品与发酵工业, 2020 , 46(21) : 262 -271 . DOI: 10.13995/j.cnki.11-1802/ts.024540

Abstract

Malignant tumor is a serious threat to human health. Its incidence rate and mortality rate are also increased year by year. In recent years, natural seaweeds have been used to obtain bioactive peptides which with high efficiency and low toxicity. Therefore, the antitumor activity of bioactive peptides derived from seaweeds has gradually attracted the attention of researchers. This paper reviewed the common kinds and preparation methods of seaweed bioactive peptides. Meanwhile, the evaluation methods and mechanism of seaweed antitumor active peptides were also been described, so as to provide reference for the development of antitumor natural drugs and foods.

Key words： seaweed; antitumor active peptides; activity evaluation; mechanism

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